Swagat S. Pradhan
@swagatspradhan.bsky.social
Doctoral Student at University of Helsinki @Asw_lab @HelsinkiUni | 🔬Keen interest in Mitochondrial biology and other cryptics of nature| 📚Avid reader 🇫🇮🇮🇳
5/5 Detailed microscopic analysis using mitoQC by Takayuki Mito shows fiber-specific stalled autophagy/mitophagy in both EOMs and quadriceps.
July 19, 2025 at 10:31 AM
5/5 Detailed microscopic analysis using mitoQC by Takayuki Mito shows fiber-specific stalled autophagy/mitophagy in both EOMs and quadriceps.
4/5 PDK4 is highly upregulated in EOMs, inhibiting glucose oxidation and pushing a shift toward fatty acid metabolism.
July 19, 2025 at 10:31 AM
4/5 PDK4 is highly upregulated in EOMs, inhibiting glucose oxidation and pushing a shift toward fatty acid metabolism.
3/5 EOMs and quadriceps respond remarkably distinctly to mitochondrial stress. Quadriceps activate ISRmt and anabolic pathways; EOMs do not.
#mitochondria #myopathy #stressresponses
#mitochondria #myopathy #stressresponses
July 19, 2025 at 10:31 AM
3/5 EOMs and quadriceps respond remarkably distinctly to mitochondrial stress. Quadriceps activate ISRmt and anabolic pathways; EOMs do not.
#mitochondria #myopathy #stressresponses
#mitochondria #myopathy #stressresponses