suwebreza.bsky.social
@suwebreza.bsky.social
January 27, 2026 at 10:23 AM
Loss-of-function mutations in PLD4 linked to SLE:

🔬 PLD4 mutations led to high TLR7/9 activation
🔬 5 patients showed reduced exonuclease activity
🔬 Effective baricitinib treatment in mice

#SLE #Genetics #Inflammation #Pub2Post
https://tnyp.me/vwTf6xf5/s
January 22, 2026 at 5:00 PM
"Re: Testosterone Therapy Guidelines"
📉Single biochemical thresholds oversimplify
🧠Tailoring cutoffs to specific endpoints is crucial
📈Symptoms should guide diagnosis #Hypogonadism #Endocrinology #Pub2Post https://tnyp.me/go6OJMXm/s
January 22, 2026 at 4:59 PM
Small intracellular vesicles (sIVs):
🔬 Smaller size, higher yield
📊 5-10x protein vs. small extracellular vesicles (sEVs)
🚀 Enhanced drug delivery
#Neuroprotection #BiomedicalEngineering #Pub2Post https://tnyp.me/vsUbO3zG/s
January 22, 2026 at 4:59 PM
Newly identified RNU4-2 and RNU6 variants link to retinitis pigmentosa.

📊 Includes 153 affected individuals, 67 families.

🌍 RP affects ~2 million globally.

#Genetics #RetinitisPigmentosa #RNA #Pub2Post https://tnyp.me/JoO75rwP/s
January 22, 2026 at 4:58 PM
3D-printed models improve RCC with VTE surgical planning

🩺 Fewer ICU stays (52% 3D vs. 48% image)
🛡️ Lower severe complications (OR: 20.46 attested)

#3DPrinting #RCC #ClinicalTrial #Urology #MedicalInnovation #Pub2Post

https://tnyp.me/5PtUuN7c/s
January 22, 2026 at 4:57 PM
Glycan Shielding Enables TCR-Sufficient Allogeneic CAR-T Therapy
🔬 SPPL3 deletion enhances T cell glycosylation patterns

#CAR-T #B-NHL #CancerTherapy #Pub2Post
https://tnyp.me/FbhvQ66a/s
January 22, 2026 at 4:56 PM
Review of surgical referral systems in LMICs highlights:

📊 Streamlined coordination improves system efficiency.

#HealthSystems #LMICs #Surgery #HealthcareReform #Pub2Post

https://tnyp.me/BQ4J2biE/s
January 22, 2026 at 4:55 PM

✔️ WHO checklist usage higher in first referral (99.4%).
📉 No significant difference in 30-day mortality between hospitals.

#GlobalSurgery #HealthcareResearch #LMIC #Pub2Post
https://tnyp.me/k32Aqpbj/s
January 22, 2026 at 4:54 PM
Aeromonas variant enhances ulcerative colitis risk.

📊 CCR2⁺HLA-DR⁺ macrophages ↑ in inflamed colon
📊 Th17 cells linked to inflammation
📊 Differences in immune cell frequencies

#UlcerativeColitis #Immunology #Pub2Post https://tnyp.me/gVgDODuX/s
January 22, 2026 at 3:53 PM
Irregular Diet and Esophageal Cancer:

🍽️ 6 studies analyzed
📊 Found RR of 4.181 (95% CI 2.196 – 7.960)
🔬 Heterogeneity sources: non-disease, nurses, Asians

#EsophagealCancer #IrregularDiet #MetaAnalysis #Genetics #Pub2Post https://tnyp.me/gQApwmOQ/s
January 22, 2026 at 3:53 PM
Myocardial infarction influences AAV-based gene transfer.
🧬 MI enhances cardiac AAV transduction, peaking on day 3 post-MI in mice
🔬 Excessive AAV enrichment independent of serotypes
#GeneTherapy #Cardiology #AAVResearch #Pub2Post https://tnyp.me/VJ61sNPM/s
January 22, 2026 at 3:52 PM
Title: Enhancer Remodeling by OTX2 Directs Specification and Patterning of Mammalian Definitive Endoderm

🔍 OTX2 is critical for definitive endoderm patterning.

#OTX2 #DevelopmentalBiology #Endoderm #GeneRegulation #Pub2Post https://tnyp.me/s3IJY0xx/s
January 22, 2026 at 3:52 PM
Mapping sensory circuits to bone uncovers signals for healing

🧠 Studied tdT+ DRG neurons over 1-4 weeks in mice (N=3)
🔬 N=1,020 neurons analyzed from N=12 DRGs

#Neuroscience #FractureHealing #Pub2Post
https://tnyp.me/cfIIn4pb/s
January 22, 2026 at 3:51 PM
CLAIM 2024 Update:
🔍 275 PubMed, 608 Scholar citations
📈 New "Yes, No, NA" options
🔄 "Reference standard" over "ground truth"
#AI #MedicalImaging #CLAIM2024 #Pub2Post
https://tnyp.me/qI1nI0PN/s
January 22, 2026 at 3:50 PM
2025 ATA Guidelines: Differentiated Thyroid Cancer

🧪 Revised regimen covers cancer diagnosis to subsequent therapies
📊 Data-driven decisions prioritize patient journey in DTC

#ThyroidCancer #DTC #ATAGuidelines #Pub2Post

https://tnyp.me/klrDiXX5/s
January 22, 2026 at 3:48 PM
Histone variant H3.14 responds to abiotic stress in Arabidopsis:
🌱 H3.14 expressed in root transition zone
🔬 Dual role: activates stress genes, represses
More at https://tnyp.me/S0eSd1Ut/s
#Arabidopsis #StressResponse #Chromatin #H3Variant #Pub2Post
January 22, 2026 at 3:47 PM
Investigations into pseudopterosin biosynthesis in Symbiodinium sp. yield vital insights.

🧪 Symbiodinium sp. confirmed as biosynthetic source.
#Pseudopterosin #Biotech #Symbiodinium #ChemBio #Pub2Post

https://tnyp.me/jIqjitIQ/s
January 22, 2026 at 3:45 PM
Elderly emerge as the norm in emergency care.
📈 Rise of patients 85+ by 24.2% (2000–2015)
🏥 Geriatric emergency guidelines set
🧠 Focus on delirium vs. dementia

#Geriatrics #Healthcare #EmergencyMedicine #Pub2Post https://tnyp.me/gbm8TTme/s
January 21, 2026 at 1:53 PM
3D imaging tech application in robotic urologic surgery:

🧠 Enhances surgical planning
🌐 Integrates with augmented reality
📈 Optimizes educational tools

#Urology #Robotics #3DImaging #Pub2Post

https://tnyp.me/rE9OZXWZ/s
January 21, 2026 at 1:08 PM
Enzyme-based glucose delivery as a screening tool.
🍶 EnBase® Flo boosts yeast growth (OD600 ~40 AU)

#Biocatalysis #YeastResearch #EnzymeTechnology #Pub2Post
https://tnyp.me/k38fEPOS/s
January 9, 2026 at 4:02 PM
The role of UFT in metastatic colorectal cancer — by Jaafar Bennouna et al.

👉 https://tnyp.me/adsiCnrX/s
January 5, 2026 at 2:00 PM
Update on yesterday's dose-Use of delivery log-files for DAPT

🎯 Reduces positioning and anatomical errors impact.
🌐 More precise than standard therapy.
#ProtonTherapy #DAPT #Radiotherapy #Pub2Post

https://tnyp.me/dT8ZprbP/s
December 26, 2025 at 5:55 PM
Clinical predictive factors for septic arthritis of the knee in children:

🔍 Unable to bear weight
🦵 Ballottement
🩸 ESR ≥ 75 mm/h

#SepticArthritis #Pediatrics #Research #Pub2Post https://tnyp.me/rvi42hXt/s
December 23, 2025 at 8:00 AM
pub2social
"Clinical predictive factors for septic arthritis of the knee in children"
⚕️ ESR ≥ 75 mm/h
18.8% septic cases in study
#SepticArthritis #Pediatrics #Pub2Post https://tnyp.me/rvi42hXt/s
December 23, 2025 at 7:44 AM