These suggest that integration occurs along the cortical hierarchy from transmodal to unimodal brain systems, by offering a holistic interpretation of temporal dynamics in pain processing within the framework of cortical hierarchy. (7/8)

In contrast, during the mid-to-late stages of integration, the somatomotor network regions were important in mediating the effects of stimulus intensity. (6/8)

In the results of the cue model, in the early-to-mid stages of integration, regions within the frontoparietal and dorsal attention networks, such as the lateral prefrontal, premotor, and parietal cortex regions, mediated the effects of cues. (5/8)

Using this behavioral dynamic information, we examined temporal dynamics of brain mediation for the cue and stimulus effects on the continuous pain prediction ratings through temporal mediation analysis and ICA. Then, we found four main temporal domains for each model (4/8)

To capture the rating trajectories of continuous pain prediction, we devised a semicircular rating scale and found distinct temporal profiles that revealed a gradual shift in their relative importance from cognitive to sensory aspects of pain (3/8)