Subham Biswas
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subhambiswas.bsky.social
Subham Biswas
@subhambiswas.bsky.social
Core Facility Manager: High-Resolution Microscopy || PhD Student || Microtubules || Cytoskeleton || Microscopy 🔬
Biocytolab.com
Reposted by Subham Biswas
🚨Great News!🚨
Our latest preprint is now live on bioRxiv!
We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress.

Congrats @marianattom.bsky.social

www.biorxiv.org/content/10.1...
September 16, 2025 at 11:39 AM
Reposted by Subham Biswas
Have you ever wondered how microtubules withstand and respond to mechanical stress in cells?

Here we show by in vitro reconstitution assays that MAP65-1 and PRC1 promote microtubule nucleation on existing lattices, especially on those with structural irregularities linked to mechanical stress.
September 16, 2025 at 6:43 AM
Reposted by Subham Biswas
MAP65-1/PRC1 reinforces microtubules through nucleation https://www.biorxiv.org/content/10.1101/2025.09.14.676082v1
September 15, 2025 at 11:31 PM
Reposted by Subham Biswas
Are you ready for a symposium dedicated to microtubule dynamics, function, and structure? 🙌

#EESMicrotubules will bring together researchers who share an interest in microtubule biology and its relevance to health and disease 🩺

💻 s.embl.org/ees26-09-bl
✒️ Submit your abstract by 11 March
September 11, 2025 at 2:13 PM
Reposted by Subham Biswas
Kinesin-induced buckling reveals the limits of microtubule self-repair https://www.biorxiv.org/content/10.1101/2025.09.08.672697v1
September 12, 2025 at 9:48 PM
Reposted by Subham Biswas
Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳

We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.

Congratulations @subhambiswas.bsky.social!

www.nature.com/articles/s41...
September 11, 2025 at 6:03 PM
Excited to share that my paper on Tau–Microtubule interactions is now published in Nature Physics!🎉

Our work shows that tau goes beyond stabilizing microtubules—it also promotes the removal of defects in the microtubule lattice.

www.nature.com/articles/s41...
Tau accelerates tubulin exchange in the microtubule lattice - Nature Physics
Beyond its known role in stabilizing microtubules, it is now shown that tau protein actively promotes lattice defect repair by enhancing tubulin turnover at topological defects.
www.nature.com
September 9, 2025 at 11:57 AM
🚨We are hiring!!🚨
📢Our lab has two #ERC funded #PhD positions on an exciting project on cytoskeleton crosstalk to investigate how microtubules and vimentin intermediate filaments work together.

For additional details, visit: biocytolab.com/jobs/

Please share/repost!
January 23, 2024 at 1:42 PM
We have a PhD opening 🎓 at our lab in Saarbrücken, Germany!

The project focuses on interactions between microtubules and intermediate filaments in the cytoskeleton, “crosstalk”.

For additional information, visit: biocytolab.com
January 22, 2024 at 8:19 AM