Steven Gruber
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stvngrbr.bsky.social
Steven Gruber
@stvngrbr.bsky.social
22 followers 33 following 87 posts
From the Midwest to the West Coast. Fan of biking, learning, and sharing. Scientist at Illumina focused on DNA Methylation.
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stvngrbr.bsky.social
After reading this, I then read this review that UK will transition from animal testing... Just a one-two punch that hurt my brain. 🤷‍♂️🤯

Any thoughts/perspective? @urnov.bsky.social
I understand the benefits, but unclear if pros outweigh the potential risks..
www.technologyreview.com/2025/11/14/1...
These technologies could help put a stop to animal testing
Advanced in organs on chips, digital twins, and AI are ushering in a new era of research and drug development.
www.technologyreview.com
November 22, 2025 at 12:26 AM
stvngrbr.bsky.social
After reading this brilliant journey, where the animal model gave researchers confidence to readjust vector dose/concentration, I then read this review that UK will transition from animal testing... Just a one-two punch that hurt my brain. 🤷‍♂️🤯

www.technologyreview.com/2025/11/14/1...
These technologies could help put a stop to animal testing
Advanced in organs on chips, digital twins, and AI are ushering in a new era of research and drug development.
www.technologyreview.com
November 22, 2025 at 12:22 AM
stvngrbr.bsky.social
Such a journey, great write up, thanks for highlighting!
November 21, 2025 at 11:54 PM
stvngrbr.bsky.social
Update: fred.stlouisfed.org/series/USEPU...
Impressive how tariffs rival a global pandemic
October 15, 2025 at 2:15 PM
stvngrbr.bsky.social
Very excited to get my mind turned into a pretzel!
August 3, 2025 at 2:43 AM
stvngrbr.bsky.social
Is Explainable AI (XAI) a viable solution for understanding biological mechanisms? The DKFZ group reviewed their Brain Tumor Classifier epigenetic tool. Short answer, it doesn't appear to...so what next? bsky.app/profile/stvn...
stvngrbr.bsky.social Steven Gruber @stvngrbr.bsky.social · Feb 23
This is so cool. Patterns in DNA Methylation have been used for years to stratify Brain Tumors via Random Forest machine learning technique. Now, the same data with a different machine learning technique may interpret the biological meaning. "XAI" Explainable Artificial Intelligence.
July 15, 2025 at 4:56 PM
stvngrbr.bsky.social
@gutumorbiology.bsky.social
9-months ago, this post, now the paper! The internet is a cool place!
bsky.app/profile/gutu...
gutumorbiology.bsky.social GU Tumor Biology Training Program @gutumorbiology.bsky.social · Sep 12
* Anton Wellstein, M.D., Ph.D., professor of oncology and pharmacology, has helped develop a totally new technique (“liquid biopsy”) that could precisely identify the location of potential problems as early as the second week after a liver transplant.
June 20, 2025 at 4:38 PM
stvngrbr.bsky.social
GenomeWeb with a nice summary!
www.genomeweb.com/liquid-biops...
Methylation Patterns Zero in on Cell Types, Cellular Mechanisms Involved in Liver Transplant Rejection
Cell-free DNA methylation patterns identified specific cell and tissue types predictive of liver transplant rejection in a recent study.
www.genomeweb.com
June 20, 2025 at 4:35 PM