Alexey Strygin
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strygah.bsky.social
Alexey Strygin
@strygah.bsky.social
founder, executive, vitalist 🧬 longevity biotech, longevity economics, drug discovery, startups
Is it just me, or am I uncovering new reasons to pursue radical life extension? 🤔

(Of course, we're talking about biological age in theoretical high calendar-year-old 25-year-olds!)

Paper for reference:
doi.org/10.1101/cshp...
International Gains to Achieving Healthy Longevity
doi.org
December 4, 2024 at 5:28 PM
1️⃣ It's way better to be a woman!
2️⃣ If you're a man lucky enough to live to 5,000 years, you're in a world where there are three 25-year-old Japanese women for every one of you!
3️⃣ If you've made it to 10,000 years, the number of women per man is ~7.5.
December 4, 2024 at 5:28 PM
3️⃣ We also know there are big differences between male and female mortality rates. I found the mortality rates for 25-year-olds in Japan (0.02% for women, 0.04% for men) and plotted a graph. What do we observe?
December 4, 2024 at 5:28 PM
2️⃣ There's a huge variation in lifespan (see the survival curve I modeled):

Half the people will die before reaching 1,214.5 years
18% will live up to 3,000 years
5.78% will make it to 5,000 years
0.33% will reach 10,000 years
December 4, 2024 at 5:28 PM
1️⃣ Even when we remove aging from the equation, there are still chances of dying (from infections, violence, accidents, and cancers). For 30-year-olds, the mortality rate in the paper is about ~0.057% per year, aligning with data from developed countries like Japan.
December 4, 2024 at 5:28 PM
Reversing one year of aging per year essentially hits the Longevity Escape Velocity point. In this scenario, the expected lifespan for 30-year-olds is 1,782.6 years.

Way better than now!

But there are important nuances (I played around with the data for you): 📊
December 4, 2024 at 5:28 PM