Satoko M
@stkm22.bsky.social
Interested in clinical statistics and health economics. UCL Alumni.
Reposted by Satoko M
Regular reminder that we basically just make up what gets designated 'lower' and 'higher' order terms in regression models.
This paper isn't constructive but is fun. Don't rely on the marginality principle!
@maartenvsmeden.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
This paper isn't constructive but is fun. Don't rely on the marginality principle!
@maartenvsmeden.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
The marginality principle revisited: Should “higher‐order” terms always be accompanied by “lower‐order” terms in regression analyses?
The marginality principle guides analysts to avoid omitting lower-order terms from models in which higher-order terms are included as covariates. Lower-order terms are viewed as “marginal” to higher-...
onlinelibrary.wiley.com
December 18, 2024 at 1:13 PM
Regular reminder that we basically just make up what gets designated 'lower' and 'higher' order terms in regression models.
This paper isn't constructive but is fun. Don't rely on the marginality principle!
@maartenvsmeden.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
This paper isn't constructive but is fun. Don't rely on the marginality principle!
@maartenvsmeden.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Satoko M
I did a calculation a few months ago and the federal government has invested 70+B dollars in biomarker discovery most of which fails to yield actionable insights. This is well after David Rasnahoff warned everyone of the challenges in the science of biomarker validation starting 2007.
Predict != Usefully Predict.
I'll bet that in the next 3 years we'll have a few hundred papers on micobiome + machine learning to predict long covid + some cluster analysis, and zero of them will lead to clinically useful insights.
I'll bet that in the next 3 years we'll have a few hundred papers on micobiome + machine learning to predict long covid + some cluster analysis, and zero of them will lead to clinically useful insights.
Gut Microbiome Signatures During Acute Infection Predict Long COVID https://www.biorxiv.org/content/10.1101/2024.12.10.626852v1
December 12, 2024 at 2:20 PM
I did a calculation a few months ago and the federal government has invested 70+B dollars in biomarker discovery most of which fails to yield actionable insights. This is well after David Rasnahoff warned everyone of the challenges in the science of biomarker validation starting 2007.
Reposted by Satoko M
Predict != Usefully Predict.
I'll bet that in the next 3 years we'll have a few hundred papers on micobiome + machine learning to predict long covid + some cluster analysis, and zero of them will lead to clinically useful insights.
I'll bet that in the next 3 years we'll have a few hundred papers on micobiome + machine learning to predict long covid + some cluster analysis, and zero of them will lead to clinically useful insights.
Gut Microbiome Signatures During Acute Infection Predict Long COVID https://www.biorxiv.org/content/10.1101/2024.12.10.626852v1
December 12, 2024 at 3:12 AM
Predict != Usefully Predict.
I'll bet that in the next 3 years we'll have a few hundred papers on micobiome + machine learning to predict long covid + some cluster analysis, and zero of them will lead to clinically useful insights.
I'll bet that in the next 3 years we'll have a few hundred papers on micobiome + machine learning to predict long covid + some cluster analysis, and zero of them will lead to clinically useful insights.
Reposted by Satoko M
🚀 Thrilled to share our latest research! Our new study introduces an innovative computational tool using our Tocky technology to decipher time-dependent processes in cellular development.
journals.biologists.com/dev/article/...
@dev-journal.bsky.social
journals.biologists.com/dev/article/...
@dev-journal.bsky.social
December 1, 2024 at 8:55 PM
🚀 Thrilled to share our latest research! Our new study introduces an innovative computational tool using our Tocky technology to decipher time-dependent processes in cellular development.
journals.biologists.com/dev/article/...
@dev-journal.bsky.social
journals.biologists.com/dev/article/...
@dev-journal.bsky.social
Reposted by Satoko M
制御性T細胞：免疫学コミュニティーに蔓延する病について
monotockylab.github.io/japanese/202...
1980年代から始まったTreg研究の歴史と、その中で免疫学コミュニティーに蔓延していく「病」がどのような影響を与えていったのか、そして私自身の研究がどのようにこの問題に対応してきたかについて書きます
#免疫学会
monotockylab.github.io/japanese/202...
1980年代から始まったTreg研究の歴史と、その中で免疫学コミュニティーに蔓延していく「病」がどのような影響を与えていったのか、そして私自身の研究がどのようにこの問題に対応してきたかについて書きます
#免疫学会
Masahiro Ono | 制御性T細胞：免疫学コミュニティーに蔓延する病について
制御性T細胞の根幹理論について再考する
monotockylab.github.io
December 2, 2024 at 11:51 PM
制御性T細胞：免疫学コミュニティーに蔓延する病について
monotockylab.github.io/japanese/202...
1980年代から始まったTreg研究の歴史と、その中で免疫学コミュニティーに蔓延していく「病」がどのような影響を与えていったのか、そして私自身の研究がどのようにこの問題に対応してきたかについて書きます
#免疫学会
monotockylab.github.io/japanese/202...
1980年代から始まったTreg研究の歴史と、その中で免疫学コミュニティーに蔓延していく「病」がどのような影響を与えていったのか、そして私自身の研究がどのようにこの問題に対応してきたかについて書きます
#免疫学会