A new review just out with John Diffley and Janet Iwasa provides high resolution videos of the earliest stages of DNA replication in eukaryotes, the formation of pre-Replicative Complexes. Comparison of mechanisms in yeast and human cells is presented. See rdcu.be/et5Uh
Mechanisms for licensing origins of DNA replication in eukaryotic cells
Nature Structural & Molecular Biology - Here, the authors comprehensively discuss the different mechanisms for origin licensing in yeast and human cells. Importantly, they present intuitive...
rdcu.be
July 3, 2025 at 4:18 PM
A new review just out with John Diffley and Janet Iwasa provides high resolution videos of the earliest stages of DNA replication in eukaryotes, the formation of pre-Replicative Complexes. Comparison of mechanisms in yeast and human cells is presented. See rdcu.be/et5Uh