Stefanie Kühn
steffi-k.bsky.social
Stefanie Kühn
@steffi-k.bsky.social
Reposted by Stefanie Kühn
Teaching an old bacterial protein new tricks: Fast, bright and reversible rhodamine tags for live-cell imaging:

www.biorxiv.org/content/10.1...

Congratulations to Julian Kompa and the entire team.
Fast, Bright and Reversible Rhodamine Tags for Live-Cell Imaging
We present Rho-tag and SiR-tag, engineered protein tags derived from bacterial multidrug-resistance proteins that bind unsubstituted (silicon-) rhodamines with nanomolar affinity, enabling fast, rever...
www.biorxiv.org
July 9, 2025 at 7:58 PM
Reposted by Stefanie Kühn
Molecular recording of cellular protein kinase activity with chemical labeling:

www.nature.com/articles/s41...

Congratulations to De-en Sun and the entire team.
Molecular recording of cellular protein kinase activity with chemical labeling - Nature Chemical Biology
Molecular recorders based on kinase activity-dependent protein labeling track specific kinase activities to understand their link to cellular phenotypes in heterogeneous cell populations and in vivo.
www.nature.com
July 10, 2025 at 5:46 PM
🚨 Paper alert: SNAP-tag2 for faster and brighter protein labeling

I am more than happy to see the core results of my PhD finally published in Nature Chem.Bio. 🎉

Big thanks to everyone who contributed to this work and supported it along the way. 😊

And I hope you'll have fun using SNAP-Tag2 now!🔬
July 3, 2025 at 8:15 PM
Reposted by Stefanie Kühn
Please check out our new high-affinity split-HaloTag for live-cell protein labeling www.biorxiv.org/content/10.1...
Congratulations to Yin-Hsi Lin!
www.biorxiv.org
June 16, 2025 at 2:24 PM