St. Anna Children's Cancer Research Institute (CCRI)
@stanna-ccri.bsky.social
St. Anna CCRI is developing and optimizing diagnostic, prognostic and therapeutic strategies for the treatment of children suffering from cancer.
How can Europe turn rare disease challenges into coordinated solutions? At the European Health Summit, Prof. Ruth Ladenstein highlighted how cross-border collaboration can improve diagnosis, research and access to care for children with rare diseases like childhood cancer. vimeo.com/1142443149?s...
December 3, 2025 at 3:53 PM
How can Europe turn rare disease challenges into coordinated solutions? At the European Health Summit, Prof. Ruth Ladenstein highlighted how cross-border collaboration can improve diagnosis, research and access to care for children with rare diseases like childhood cancer. vimeo.com/1142443149?s...
Reposted by St. Anna Children's Cancer Research Institute (CCRI)
🧬 New strategy to fight #AML: A study led by @floriangrebien.bsky.social & team at Vetmeduni, @stanna-ccri.bsky.social & CeMM identified the protein SPOP as a direct regulator of the stability of NUP98 fusion oncoproteins, a potential target for new therapies.
➡️ bit.ly/3M2RfWz
📄 bit.ly/4omtZ3x
➡️ bit.ly/3M2RfWz
📄 bit.ly/4omtZ3x
November 28, 2025 at 7:31 AM
🧬 New strategy to fight #AML: A study led by @floriangrebien.bsky.social & team at Vetmeduni, @stanna-ccri.bsky.social & CeMM identified the protein SPOP as a direct regulator of the stability of NUP98 fusion oncoproteins, a potential target for new therapies.
➡️ bit.ly/3M2RfWz
📄 bit.ly/4omtZ3x
➡️ bit.ly/3M2RfWz
📄 bit.ly/4omtZ3x
Great discussions with the LCH community at this year’s ECHO Meeting in Florence! 🌟
With presentations on high-risk LCH trial design, iPSC models, and preliminary LCH-IV results, our team was glad to be part of this scientific exchange.
With presentations on high-risk LCH trial design, iPSC models, and preliminary LCH-IV results, our team was glad to be part of this scientific exchange.
November 21, 2025 at 3:47 PM
Great discussions with the LCH community at this year’s ECHO Meeting in Florence! 🌟
With presentations on high-risk LCH trial design, iPSC models, and preliminary LCH-IV results, our team was glad to be part of this scientific exchange.
With presentations on high-risk LCH trial design, iPSC models, and preliminary LCH-IV results, our team was glad to be part of this scientific exchange.
Members of the Seruggia and Tomazou groups attended “When Development Meets Cancer” at IRB Barcelona this week! 👏 Talks by Hannah Beneder & Ornella Urzì, posters by Tamina Stelzer, Manon Ressaire & Hana Bernhardova, a fantastic representation from both teams!
November 13, 2025 at 11:36 AM
Members of the Seruggia and Tomazou groups attended “When Development Meets Cancer” at IRB Barcelona this week! 👏 Talks by Hannah Beneder & Ornella Urzì, posters by Tamina Stelzer, Manon Ressaire & Hana Bernhardova, a fantastic representation from both teams!
Congrats to Sara Wernig-Zorc for completing the Clinical Trials program at Harvard Medical School, with distinction! 🎓👏 Her capstone on biomarker-driven immunotherapy in neuroblastoma was recognized for excellence. #ClinicalResearch #HarvardMed #Neuroblastoma ©Liesl Clark
November 12, 2025 at 9:48 AM
Congrats to Sara Wernig-Zorc for completing the Clinical Trials program at Harvard Medical School, with distinction! 🎓👏 Her capstone on biomarker-driven immunotherapy in neuroblastoma was recognized for excellence. #ClinicalResearch #HarvardMed #Neuroblastoma ©Liesl Clark
We are proud to see Peter Peneder, formerly with the Tomazou group, contributing to such an impressive project!
🗨️Chat with your cells, explore #CellWhisperer!
CeMM PI Christoph Bock (@bocklab.bsky.social) together with @meduniwien.ac.at & @stanna-ccri.bsky.social have developed a new #AI tool that lets scientists explore single-cell data using plain English.
➡️ https://bit.ly/3JQqe87
📄 https://bit.ly/3WJCxGi
CeMM PI Christoph Bock (@bocklab.bsky.social) together with @meduniwien.ac.at & @stanna-ccri.bsky.social have developed a new #AI tool that lets scientists explore single-cell data using plain English.
➡️ https://bit.ly/3JQqe87
📄 https://bit.ly/3WJCxGi
November 11, 2025 at 10:29 AM
We are proud to see Peter Peneder, formerly with the Tomazou group, contributing to such an impressive project!
Ruth Ladenstein on stage for ERN PaedCan at today’s EUnetCCC Annual Meeting: discussing sustainability and shared solutions across EU health networks, with a dedicated ERN PaedCan booth on site. 🇪🇺 #EUnetCCC #ERNPaedCan #EUHealth
November 7, 2025 at 2:09 PM
Ruth Ladenstein on stage for ERN PaedCan at today’s EUnetCCC Annual Meeting: discussing sustainability and shared solutions across EU health networks, with a dedicated ERN PaedCan booth on site. 🇪🇺 #EUnetCCC #ERNPaedCan #EUHealth
St. Anna CCRI is pleased to announce the appointment of Eleni Tomazou and Sabine Taschner-Mandl, two internationally recognized experts, as new Scientific Directors. 🔗Read more: lnkd.in/gKF_cJFM
October 29, 2025 at 2:38 PM
St. Anna CCRI is pleased to announce the appointment of Eleni Tomazou and Sabine Taschner-Mandl, two internationally recognized experts, as new Scientific Directors. 🔗Read more: lnkd.in/gKF_cJFM
Great to have Peter Kharchenko (ISTA and MedUni Vienna) with us for a guest lecture on using scRNA-seq data to study CNAs in cancer and normal tissues — highlighting how computational analysis helps decode tumor heterogeneity and disease mechanisms.
October 23, 2025 at 7:42 AM
Great to have Peter Kharchenko (ISTA and MedUni Vienna) with us for a guest lecture on using scRNA-seq data to study CNAs in cancer and normal tissues — highlighting how computational analysis helps decode tumor heterogeneity and disease mechanisms.
Reposted by St. Anna Children's Cancer Research Institute (CCRI)
🧬A new Science Immunology study by CeMM, @stanna-ccri.bsky.social, @meduniwien.ac.at, @medunigraz.at & @unibonn.bsky.social uncovers a surprising link between lipid biology & immune defense, with insights for rare immune disorders & cancer immunotherapy.
➡️ tinyurl.com/2ant228p
📄 tinyurl.com/yrbzt7st
➡️ tinyurl.com/2ant228p
📄 tinyurl.com/yrbzt7st
October 20, 2025 at 8:37 AM
🧬A new Science Immunology study by CeMM, @stanna-ccri.bsky.social, @meduniwien.ac.at, @medunigraz.at & @unibonn.bsky.social uncovers a surprising link between lipid biology & immune defense, with insights for rare immune disorders & cancer immunotherapy.
➡️ tinyurl.com/2ant228p
📄 tinyurl.com/yrbzt7st
➡️ tinyurl.com/2ant228p
📄 tinyurl.com/yrbzt7st
❓Why does a fusion oncogene cause Ewing sarcoma only in certain cells?
Hana Bernhardova from the Tomazou Lab at St. Anna CCRI, who recently received the BIF PhD Fellowship, is building a new model from pluripotent stem cells.
Details: 🔗 ccri.at/bif-fellowsh...
Hana Bernhardova from the Tomazou Lab at St. Anna CCRI, who recently received the BIF PhD Fellowship, is building a new model from pluripotent stem cells.
Details: 🔗 ccri.at/bif-fellowsh...
BIF Fellowship: Building Ewing Sarcoma Models from Scratch - St. Anna CCRI
BIF Fellowship: Building Ewing Sarcoma Models from Scratch Due to a lack of good models and an unknown cell of origin, Ewing sarcoma still poses a great puzzle in childhood cancer research. Hana Bernh...
ccri.at
October 13, 2025 at 8:41 AM
❓Why does a fusion oncogene cause Ewing sarcoma only in certain cells?
Hana Bernhardova from the Tomazou Lab at St. Anna CCRI, who recently received the BIF PhD Fellowship, is building a new model from pluripotent stem cells.
Details: 🔗 ccri.at/bif-fellowsh...
Hana Bernhardova from the Tomazou Lab at St. Anna CCRI, who recently received the BIF PhD Fellowship, is building a new model from pluripotent stem cells.
Details: 🔗 ccri.at/bif-fellowsh...
✨ Guest lectures are an important part of how we foster scientific exchange at St. Anna CCRI. This week we had the pleasure of hosting Jose Tubio (CiMUS, Spain), who spoke on the impact of mobile DNA in human cancer and disease.
@mobilegenomes.bsky.social
@cimususc.bsky.social
@mobilegenomes.bsky.social
@cimususc.bsky.social
October 3, 2025 at 7:20 AM
✨ Guest lectures are an important part of how we foster scientific exchange at St. Anna CCRI. This week we had the pleasure of hosting Jose Tubio (CiMUS, Spain), who spoke on the impact of mobile DNA in human cancer and disease.
@mobilegenomes.bsky.social
@cimususc.bsky.social
@mobilegenomes.bsky.social
@cimususc.bsky.social
We were invited to TedAI in the Hofburg, Vienna to show how AI is supporting childhood cancer research.🔬 Peter Zöscher presented how the AI tool developed by Simon Gutwein (Taschner-Mandl group) flags suspicious cells & speeds up diagnostics.
September 26, 2025 at 1:16 PM
We were invited to TedAI in the Hofburg, Vienna to show how AI is supporting childhood cancer research.🔬 Peter Zöscher presented how the AI tool developed by Simon Gutwein (Taschner-Mandl group) flags suspicious cells & speeds up diagnostics.
Thank you to Jan Škoda (@skodalab.bsky.social from Masaryk Univ & ICRC Brno) for an inspiring guest lecture on repurposing drugs for mitochondria-targeted therapies in MYC-driven pediatric tumors, highlighting new strategies to overcome therapy resistance in cancers such as high-risk neuroblastoma.
September 24, 2025 at 12:21 PM
Thank you to Jan Škoda (@skodalab.bsky.social from Masaryk Univ & ICRC Brno) for an inspiring guest lecture on repurposing drugs for mitochondria-targeted therapies in MYC-driven pediatric tumors, highlighting new strategies to overcome therapy resistance in cancers such as high-risk neuroblastoma.
👏 We are proud to see Kaan Boztug, PI at St. Anna CCRI, and Irinka Castanon, senior researcher in the Boztug Group, at the forefront of this new review in Nature Reviews Immunology.
📘 New #publication! The group of @boztugk.bsky.social published a #review #article titled "Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation" in Nature Reviews Immunology.
Read more in the news article: www.immunosensation.de/news/how-cel...
Read more in the news article: www.immunosensation.de/news/how-cel...
September 22, 2025 at 12:22 PM
👏 We are proud to see Kaan Boztug, PI at St. Anna CCRI, and Irinka Castanon, senior researcher in the Boztug Group, at the forefront of this new review in Nature Reviews Immunology.
How can therapy resistance in childhood AML be detected already at diagnosis❓
👉Researchers from St. Anna CCRI, @cemm.oeaw.ac.at , @meduniwien.ac.at and St. Anna Kinderspital developed a new method combining imaging, molecular profiling & AI.
🔗 More info: tinyurl.com/dkc68nj6
👉Researchers from St. Anna CCRI, @cemm.oeaw.ac.at , @meduniwien.ac.at and St. Anna Kinderspital developed a new method combining imaging, molecular profiling & AI.
🔗 More info: tinyurl.com/dkc68nj6
Better Therapy Selection for Childhood Leukemia - St. Anna CCRI
Better Therapy Selection for Childhood Leukemia Despite decades of optimization of treatment protocols, the prognosis for acute myeloid leukemia in children (pediatric AML, pedAML) remains poor for ma...
tinyurl.com
September 22, 2025 at 8:14 AM
How can therapy resistance in childhood AML be detected already at diagnosis❓
👉Researchers from St. Anna CCRI, @cemm.oeaw.ac.at , @meduniwien.ac.at and St. Anna Kinderspital developed a new method combining imaging, molecular profiling & AI.
🔗 More info: tinyurl.com/dkc68nj6
👉Researchers from St. Anna CCRI, @cemm.oeaw.ac.at , @meduniwien.ac.at and St. Anna Kinderspital developed a new method combining imaging, molecular profiling & AI.
🔗 More info: tinyurl.com/dkc68nj6
Wrapping up a successful SIOPEN AGM Meeting! 4 presentations, 1 award (congrats Sören Strohmenger 🎉) and a dedicated MONALISA meeting:
✅Liquid biopsy tests ready in 7 reference labs across Europe (incl. accredited tests at Labdia)
✅ clinical trial set to open by end of 2025
✅Liquid biopsy tests ready in 7 reference labs across Europe (incl. accredited tests at Labdia)
✅ clinical trial set to open by end of 2025
September 19, 2025 at 2:22 PM
Wrapping up a successful SIOPEN AGM Meeting! 4 presentations, 1 award (congrats Sören Strohmenger 🎉) and a dedicated MONALISA meeting:
✅Liquid biopsy tests ready in 7 reference labs across Europe (incl. accredited tests at Labdia)
✅ clinical trial set to open by end of 2025
✅Liquid biopsy tests ready in 7 reference labs across Europe (incl. accredited tests at Labdia)
✅ clinical trial set to open by end of 2025
How can genomic discoveries improve diagnostics for children with cancer? 🌟This week, Lennart Kester (@themaximacenter.bsky.social ) gave a guest lecture at St. Anna CCRI to share how research can be translated into clinical practice.
September 17, 2025 at 1:12 PM
How can genomic discoveries improve diagnostics for children with cancer? 🌟This week, Lennart Kester (@themaximacenter.bsky.social ) gave a guest lecture at St. Anna CCRI to share how research can be translated into clinical practice.
🎓💛St. Anna CCRI is opening its doors to young people who want to explore career opportunities in pediatric cancer research. Whether you are a Bioinformatician, a Master’s, or PhD student, a Technical Assistant, or a Biomedical Analyst – this event is for you.
Register now >>> ccri.at/careers/
Register now >>> ccri.at/careers/
September 16, 2025 at 9:23 AM
🎓💛St. Anna CCRI is opening its doors to young people who want to explore career opportunities in pediatric cancer research. Whether you are a Bioinformatician, a Master’s, or PhD student, a Technical Assistant, or a Biomedical Analyst – this event is for you.
Register now >>> ccri.at/careers/
Register now >>> ccri.at/careers/
Clarity in science matters! 🧬🎨
After last year’s success, we once again hosted the workshop on “Applying Design Principles to Schematic Figures” where design expert Sandra Krahl taught our researchers how to turn complex concepts into compelling visual stories.
After last year’s success, we once again hosted the workshop on “Applying Design Principles to Schematic Figures” where design expert Sandra Krahl taught our researchers how to turn complex concepts into compelling visual stories.
September 12, 2025 at 7:34 AM
Clarity in science matters! 🧬🎨
After last year’s success, we once again hosted the workshop on “Applying Design Principles to Schematic Figures” where design expert Sandra Krahl taught our researchers how to turn complex concepts into compelling visual stories.
After last year’s success, we once again hosted the workshop on “Applying Design Principles to Schematic Figures” where design expert Sandra Krahl taught our researchers how to turn complex concepts into compelling visual stories.
Four St. Anna CCRI scientists were honored by the Austrian Society of Pediatrics & Adolescent Medicine (ÖGKJ) for outstanding publications – a special honor to receive during #ChildhoodCancerAwarenessMonth 💛
Congrats to Leo Kager, Kaan Boztug, Chantal Lucini & Florian Halbritter!
Congrats to Leo Kager, Kaan Boztug, Chantal Lucini & Florian Halbritter!
September 11, 2025 at 10:54 AM
Four St. Anna CCRI scientists were honored by the Austrian Society of Pediatrics & Adolescent Medicine (ÖGKJ) for outstanding publications – a special honor to receive during #ChildhoodCancerAwarenessMonth 💛
Congrats to Leo Kager, Kaan Boztug, Chantal Lucini & Florian Halbritter!
Congrats to Leo Kager, Kaan Boztug, Chantal Lucini & Florian Halbritter!
Join us at the St. Anna CCRI Symposium on Cell Fate in Cancer and Development and meet with top experts! Register now >>> ccri.at/st-anna-ccri-symposium-2026
🗓 January 23, 2026 14:00-18:00
📍 Van Swieten Saal, Medical University of Vienna
🗓 January 23, 2026 14:00-18:00
📍 Van Swieten Saal, Medical University of Vienna
September 11, 2025 at 10:37 AM
Join us at the St. Anna CCRI Symposium on Cell Fate in Cancer and Development and meet with top experts! Register now >>> ccri.at/st-anna-ccri-symposium-2026
🗓 January 23, 2026 14:00-18:00
📍 Van Swieten Saal, Medical University of Vienna
🗓 January 23, 2026 14:00-18:00
📍 Van Swieten Saal, Medical University of Vienna
September is Childhood Cancer Awareness Month.🎗️ Fittingly, the EU Commission/HaDEA highlights our MONALISA project, aiming to improve care for children with relapsed neuroblastoma, with insights from co-scientific project leader Sabine Taschner-Mandl.
🔗 hadea.ec.europa.eu/news/monalis...
🔗 hadea.ec.europa.eu/news/monalis...
MONALISA project: developing less invasive monitoring systems for neuroblastoma through EU Cancer Mission funding
At the occasion of Childhood Cancer Awareness Month, observed annually in September, HaDEA has reached out to the Horizon Europe project MONALISA, funded under the EU Cancer Mission.
hadea.ec.europa.eu
September 8, 2025 at 11:21 AM
September is Childhood Cancer Awareness Month.🎗️ Fittingly, the EU Commission/HaDEA highlights our MONALISA project, aiming to improve care for children with relapsed neuroblastoma, with insights from co-scientific project leader Sabine Taschner-Mandl.
🔗 hadea.ec.europa.eu/news/monalis...
🔗 hadea.ec.europa.eu/news/monalis...
Conventional methods miss ~ 60% of cases with minimal residual disease in high-risk neuroblastoma patients. A new study by Sabine Taschner-Mandl (St. Anna CCRI), Labdia and the Princess Máxima Center shows that combining three analysis methods detects these hidden tumor cells far more sensitively.
Sensitive detection of minimal residual disease and immunotherapy targets by multi-modal bone marrow analysis in high-risk neuroblastoma – a multi-center study - Journal of Experimental & Clinical Can...
Background Bone marrow dissemination of tumor cells, common in various cancers, including neuroblastoma, is associated with poor outcome, necessitating sensitive detection methods for bone marrow mini...
tinyurl.com
September 4, 2025 at 10:06 AM
Conventional methods miss ~ 60% of cases with minimal residual disease in high-risk neuroblastoma patients. A new study by Sabine Taschner-Mandl (St. Anna CCRI), Labdia and the Princess Máxima Center shows that combining three analysis methods detects these hidden tumor cells far more sensitively.
🎉 Congratulations to Mohamed Shoeb on successfully defending his PhD! Just days after the publication of his latest paper on pediatric AML, Mohamed reached another major milestone. A proud moment for the Halbritter Group (ccri.at/research-gro...) and all collaborators!
September 3, 2025 at 2:53 PM
🎉 Congratulations to Mohamed Shoeb on successfully defending his PhD! Just days after the publication of his latest paper on pediatric AML, Mohamed reached another major milestone. A proud moment for the Halbritter Group (ccri.at/research-gro...) and all collaborators!