Stan Yatskevich
stanislauy.bsky.social
Stan Yatskevich
@stanislauy.bsky.social
Post-doctoral Research Fellow at Genentech
The figure was made by @falconierivisuals.bsky.social, so credit for that goes to her
July 18, 2025 at 4:35 AM
We also discovered 4 previously uncharacterised proteins, which we named centromeric subunits 1-4 (CS module), surprisingly repurposed from the outer kinetochore Dam1/DASH complex. It will be very interesting to see how many other species contain this CS module
July 15, 2025 at 4:49 PM
Holocentric kinetochore assembles into a self-contained, head-to-head dimers that entrap and loop DNA, creating a point-centromere-like architecture, suggesting that kinetochores might assemble into such foundational "unit modules" to drive diverse centromere architectures across species
July 15, 2025 at 4:39 PM