Sinead Stoneman
@sstoneman.bsky.social
🇮🇪 Nephrologist. GN fellow in 🇨🇦.
Congratulations to @skaushal021, a 🇨🇦 medical student at 🇮🇪 @UCC presenting her poster at 🇺🇸#KidneyWk.
Collaborating with @adeeralevin and Dr Peter Birks on PCP perspectives on follow-up and guidance after hospitalisation with AKI.
Very interesting findings 👏 @UBCNephrology
Collaborating with @adeeralevin and Dr Peter Birks on PCP perspectives on follow-up and guidance after hospitalisation with AKI.
Very interesting findings 👏 @UBCNephrology
November 22, 2024 at 8:53 AM
Congratulations to @skaushal021, a 🇨🇦 medical student at 🇮🇪 @UCC presenting her poster at 🇺🇸#KidneyWk.
Collaborating with @adeeralevin and Dr Peter Birks on PCP perspectives on follow-up and guidance after hospitalisation with AKI.
Very interesting findings 👏 @UBCNephrology
Collaborating with @adeeralevin and Dr Peter Birks on PCP perspectives on follow-up and guidance after hospitalisation with AKI.
Very interesting findings 👏 @UBCNephrology
Dr Mark Elliott nephrologist at @UBCNephrology @BCRenal presenting work with @CureGn on use of ML in FSGS to integrate clinical, demographic, genetic and pathological data to identify protective and risk predictive factors.
iAUC of full model 0.95.
#kidneywk
iAUC of full model 0.95.
#kidneywk
November 22, 2024 at 8:53 AM
Dr Mark Elliott nephrologist at @UBCNephrology @BCRenal presenting work with @CureGn on use of ML in FSGS to integrate clinical, demographic, genetic and pathological data to identify protective and risk predictive factors.
iAUC of full model 0.95.
#kidneywk
iAUC of full model 0.95.
#kidneywk
#ERA24 Plenary from @BNHorowitzMD
By moving beyond humans and disease models can we improve our understanding of the causes of disease and improve biomedical innovation?
By moving beyond humans and disease models can we improve our understanding of the causes of disease and improve biomedical innovation?
November 22, 2024 at 9:04 AM
#ERA24 Plenary from @BNHorowitzMD
By moving beyond humans and disease models can we improve our understanding of the causes of disease and improve biomedical innovation?
By moving beyond humans and disease models can we improve our understanding of the causes of disease and improve biomedical innovation?
.@IgAN_JBarratt says that for much of past 20 years trial landscape in IgAN has been 🌵resembling the sole remaining glomerulus in patients with IgAN.
This has been transformed by academic nephrologists and community pushing for change.
#ERA24
This has been transformed by academic nephrologists and community pushing for change.
#ERA24
November 22, 2024 at 9:09 AM
.@IgAN_JBarratt says that for much of past 20 years trial landscape in IgAN has been 🌵resembling the sole remaining glomerulus in patients with IgAN.
This has been transformed by academic nephrologists and community pushing for change.
#ERA24
This has been transformed by academic nephrologists and community pushing for change.
#ERA24
November 22, 2024 at 9:09 AM
How do we define disease activity in AAV?
Activity and remission as per BVAS.
https://ukivas.ndorms.ox.ac.uk/bvas
#vasculitisBCN2024
Activity and remission as per BVAS.
https://ukivas.ndorms.ox.ac.uk/bvas
#vasculitisBCN2024
November 22, 2024 at 9:26 AM
How do we define disease activity in AAV?
Activity and remission as per BVAS.
https://ukivas.ndorms.ox.ac.uk/bvas
#vasculitisBCN2024
Activity and remission as per BVAS.
https://ukivas.ndorms.ox.ac.uk/bvas
#vasculitisBCN2024
This is just one conference in one year. We travel to many in a year and over the course of a career.
How can we do better?
There aren’t necessarily easy solutions. Visibility and discussion is a first step. Interested to hear what people think about this subject.
5/
How can we do better?
There aren’t necessarily easy solutions. Visibility and discussion is a first step. Interested to hear what people think about this subject.
5/
November 22, 2024 at 9:56 AM
This is just one conference in one year. We travel to many in a year and over the course of a career.
How can we do better?
There aren’t necessarily easy solutions. Visibility and discussion is a first step. Interested to hear what people think about this subject.
5/
How can we do better?
There aren’t necessarily easy solutions. Visibility and discussion is a first step. Interested to hear what people think about this subject.
5/
But the climate is an emergency just like COVID-19 - posing bigger threats though they might feel less tangible, deferred as a problem for the future.
Our behaviour now however has implications for the future.
4/
Our behaviour now however has implications for the future.
4/
November 22, 2024 at 9:51 AM
But the climate is an emergency just like COVID-19 - posing bigger threats though they might feel less tangible, deferred as a problem for the future.
Our behaviour now however has implications for the future.
4/
Our behaviour now however has implications for the future.
4/
We estimated that the carbon footprint from airplane travel from attendees travelling to #ERA23 was 5808 tons.
This is the equivalent of 356 SUVs driving around the world or the annual carbon footprint of 807 Europeans.
Read more here:...
This is the equivalent of 356 SUVs driving around the world or the annual carbon footprint of 807 Europeans.
Read more here:...
November 22, 2024 at 9:32 AM
We estimated that the carbon footprint from airplane travel from attendees travelling to #ERA23 was 5808 tons.
This is the equivalent of 356 SUVs driving around the world or the annual carbon footprint of 807 Europeans.
Read more here:...
This is the equivalent of 356 SUVs driving around the world or the annual carbon footprint of 807 Europeans.
Read more here:...
The climate is changing and poses the biggest global threat to human health.
Much attention has been brought to the complex interrelationship between healthcare and climate change.
Nephrology has a carbon footprint too.
But what about our own?
1/
Much attention has been brought to the complex interrelationship between healthcare and climate change.
Nephrology has a carbon footprint too.
But what about our own?
1/
November 22, 2024 at 9:26 AM
The climate is changing and poses the biggest global threat to human health.
Much attention has been brought to the complex interrelationship between healthcare and climate change.
Nephrology has a carbon footprint too.
But what about our own?
1/
Much attention has been brought to the complex interrelationship between healthcare and climate change.
Nephrology has a carbon footprint too.
But what about our own?
1/
The need for cardionephrology is established.
The question is not should we but moving towards could we, can we and will we?
@PlantLiam
#KidneyWk
The question is not should we but moving towards could we, can we and will we?
@PlantLiam
#KidneyWk
November 22, 2024 at 10:02 AM
The need for cardionephrology is established.
The question is not should we but moving towards could we, can we and will we?
@PlantLiam
#KidneyWk
The question is not should we but moving towards could we, can we and will we?
@PlantLiam
#KidneyWk
What do we know about mood changes in patients with GN on high dose corticosteroids?
Prospective study
30 patients w primary GN.
43% prior psychiatric dx.
⬆️ in mania scores seen early; depression at later stages.
From @fearghusD @MichelleOShaug3 @sarah_m_moran
#KidneyWk
Prospective study
30 patients w primary GN.
43% prior psychiatric dx.
⬆️ in mania scores seen early; depression at later stages.
From @fearghusD @MichelleOShaug3 @sarah_m_moran
#KidneyWk
November 22, 2024 at 9:56 AM
What do we know about mood changes in patients with GN on high dose corticosteroids?
Prospective study
30 patients w primary GN.
43% prior psychiatric dx.
⬆️ in mania scores seen early; depression at later stages.
From @fearghusD @MichelleOShaug3 @sarah_m_moran
#KidneyWk
Prospective study
30 patients w primary GN.
43% prior psychiatric dx.
⬆️ in mania scores seen early; depression at later stages.
From @fearghusD @MichelleOShaug3 @sarah_m_moran
#KidneyWk
🇮🇪 Retrospective cohort study
🗓️ 2011 - 2021
Kidney transplant recipients in first year post transplant
BK surveillance in 99% of patients
BK viraemia in 14%
Higher rates in males, no difference in graft survival
@michellec9999 @VickiSandys1 @PeterConlon5 et al
#KidneyWk
🗓️ 2011 - 2021
Kidney transplant recipients in first year post transplant
BK surveillance in 99% of patients
BK viraemia in 14%
Higher rates in males, no difference in graft survival
@michellec9999 @VickiSandys1 @PeterConlon5 et al
#KidneyWk
November 22, 2024 at 10:09 AM
🇮🇪 Retrospective cohort study
🗓️ 2011 - 2021
Kidney transplant recipients in first year post transplant
BK surveillance in 99% of patients
BK viraemia in 14%
Higher rates in males, no difference in graft survival
@michellec9999 @VickiSandys1 @PeterConlon5 et al
#KidneyWk
🗓️ 2011 - 2021
Kidney transplant recipients in first year post transplant
BK surveillance in 99% of patients
BK viraemia in 14%
Higher rates in males, no difference in graft survival
@michellec9999 @VickiSandys1 @PeterConlon5 et al
#KidneyWk
MELAS spectrum disorders.
Highly variable phenotypic expression.
Associated with proteinuria, FSGS.
Likely underdiagnosed.
@ecorneclegall
#KidneyWk
Highly variable phenotypic expression.
Associated with proteinuria, FSGS.
Likely underdiagnosed.
@ecorneclegall
#KidneyWk
November 22, 2024 at 10:21 AM
MELAS spectrum disorders.
Highly variable phenotypic expression.
Associated with proteinuria, FSGS.
Likely underdiagnosed.
@ecorneclegall
#KidneyWk
Highly variable phenotypic expression.
Associated with proteinuria, FSGS.
Likely underdiagnosed.
@ecorneclegall
#KidneyWk
#ERA23 Bingo
Multiple visual abstracts in the wild at the Pregnancy and CKD session
One from @NDTsocial
@galindozip for @Kidney_Int
@silvishah for @JASN_News
@CTeodosiu for @CJASN
Multiple visual abstracts in the wild at the Pregnancy and CKD session
One from @NDTsocial
@galindozip for @Kidney_Int
@silvishah for @JASN_News
@CTeodosiu for @CJASN
November 22, 2024 at 10:48 AM
#ERA23 Bingo
Multiple visual abstracts in the wild at the Pregnancy and CKD session
One from @NDTsocial
@galindozip for @Kidney_Int
@silvishah for @JASN_News
@CTeodosiu for @CJASN
Multiple visual abstracts in the wild at the Pregnancy and CKD session
One from @NDTsocial
@galindozip for @Kidney_Int
@silvishah for @JASN_News
@CTeodosiu for @CJASN
POCUS is here to stay.
Lots of #FOAMed resources that you can use to teach yourself.
Special mention to @NephroP for the resources he has made.
@DrBarbaTeba @FiSFerreira
Lots of #FOAMed resources that you can use to teach yourself.
Special mention to @NephroP for the resources he has made.
@DrBarbaTeba @FiSFerreira
November 22, 2024 at 11:16 AM
POCUS is here to stay.
Lots of #FOAMed resources that you can use to teach yourself.
Special mention to @NephroP for the resources he has made.
@DrBarbaTeba @FiSFerreira
Lots of #FOAMed resources that you can use to teach yourself.
Special mention to @NephroP for the resources he has made.
@DrBarbaTeba @FiSFerreira
November 22, 2024 at 11:08 AM
The VEXUS protocol.
Really useful tool for volume assessment.
https://pubmed.ncbi.nlm.nih.gov/32270297/
@DrBarbaTeba @FiSFerreira
#ERA23
Really useful tool for volume assessment.
https://pubmed.ncbi.nlm.nih.gov/32270297/
@DrBarbaTeba @FiSFerreira
#ERA23
November 22, 2024 at 11:01 AM
The VEXUS protocol.
Really useful tool for volume assessment.
https://pubmed.ncbi.nlm.nih.gov/32270297/
@DrBarbaTeba @FiSFerreira
#ERA23
Really useful tool for volume assessment.
https://pubmed.ncbi.nlm.nih.gov/32270297/
@DrBarbaTeba @FiSFerreira
#ERA23
November 22, 2024 at 10:54 AM
How can you tell the difference between Alport syndrome and TBM?
🛑 TBM is not a diagnosis, more a syndrome or pattern of injury.
Genetics is really important.
See more about P3H2 variants: https://www.jci.org/articles/view/147253
🛑 TBM is not a diagnosis, more a syndrome or pattern of injury.
Genetics is really important.
See more about P3H2 variants: https://www.jci.org/articles/view/147253
November 22, 2024 at 11:08 AM
How can you tell the difference between Alport syndrome and TBM?
🛑 TBM is not a diagnosis, more a syndrome or pattern of injury.
Genetics is really important.
See more about P3H2 variants: https://www.jci.org/articles/view/147253
🛑 TBM is not a diagnosis, more a syndrome or pattern of injury.
Genetics is really important.
See more about P3H2 variants: https://www.jci.org/articles/view/147253
What are the biopsy findings in Alport syndrome?
Classic EM findings are seen late in the disease.
- GBM thickening
- Podocyte effacement
- Basket weaving
Classic EM findings are seen late in the disease.
- GBM thickening
- Podocyte effacement
- Basket weaving
November 22, 2024 at 11:01 AM
What are the biopsy findings in Alport syndrome?
Classic EM findings are seen late in the disease.
- GBM thickening
- Podocyte effacement
- Basket weaving
Classic EM findings are seen late in the disease.
- GBM thickening
- Podocyte effacement
- Basket weaving
In a targeted population of children with at least one of low GFR, haematuria, positive family history or suspected FSGS or Alport on biopsy.
28% had a positive genetic test for Alport syndrome.
https://link.springer.com/article/10.1007/s00467-023-05993-z#MOESM1
28% had a positive genetic test for Alport syndrome.
https://link.springer.com/article/10.1007/s00467-023-05993-z#MOESM1
November 22, 2024 at 10:54 AM
In a targeted population of children with at least one of low GFR, haematuria, positive family history or suspected FSGS or Alport on biopsy.
28% had a positive genetic test for Alport syndrome.
https://link.springer.com/article/10.1007/s00467-023-05993-z#MOESM1
28% had a positive genetic test for Alport syndrome.
https://link.springer.com/article/10.1007/s00467-023-05993-z#MOESM1
Alternative pathway does not need a trigger, a more primitive system, works like a guardian of the intravascular space.
Classical pathway needs a trigger.
Classical pathway needs a trigger.
November 22, 2024 at 10:54 AM
Alternative pathway does not need a trigger, a more primitive system, works like a guardian of the intravascular space.
Classical pathway needs a trigger.
Classical pathway needs a trigger.
November 22, 2024 at 12:17 PM