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sprintome.bsky.social
Sprintome
@sprintome.bsky.social
AI + Drug Discovery | Your front-row seat to the future of medicine
https://sprintome.substack.com
Inference-time steerable generation, not just sampling.

Neo-1 drafts an entire sketch of the molecule, then iteratively refines it, so every atom can be nudged by later context. No more getting stuck with a bad first bond like in autoregressive chains.
May 25, 2025 at 5:15 PM
Neo-1, billed as “the world’s most advanced atomistic foundation model,” unifies structure prediction and all-atom de-novo generation in a single neural core.
May 25, 2025 at 5:14 PM
VantAI and Blueprint Medicines are revising their partnership to tackle "historically undruggable targets," citing the use of Neo-1, VantAI's foundation model, as key to the partnership.

The deal includes up to $1.67 Billion in future milestone payments.

So what is Neo-1? 🧵
May 25, 2025 at 5:13 PM