@special-k.bsky.social
Humanist. Scientist. Pharma-lobby.
Views are my own (but not patented ;-))
Views are my own (but not patented ;-))
Reposted
www.science.org/doi/10.1126/...
Research highlight📖
“…colonizing the gut of autoimmune-prone mice with E. gallinarum led to dissemination of living E. gallinarum to the lymph nodes, liver, and spleen, accompanied by ⬆️TH17 cells at these sites and production of anti-RNA #autoantibodies. “
Research highlight📖
“…colonizing the gut of autoimmune-prone mice with E. gallinarum led to dissemination of living E. gallinarum to the lymph nodes, liver, and spleen, accompanied by ⬆️TH17 cells at these sites and production of anti-RNA #autoantibodies. “
Trouble at the border: An invading gut bacterium can break tolerance to self-RNA
Mouse anti-RNA antibodies triggered by gut E. gallinarum correlate with self-RNA autoantibodies and lupus severity in humans.
www.science.org
March 10, 2025 at 1:39 AM
www.science.org/doi/10.1126/...
Research highlight📖
“…colonizing the gut of autoimmune-prone mice with E. gallinarum led to dissemination of living E. gallinarum to the lymph nodes, liver, and spleen, accompanied by ⬆️TH17 cells at these sites and production of anti-RNA #autoantibodies. “
Research highlight📖
“…colonizing the gut of autoimmune-prone mice with E. gallinarum led to dissemination of living E. gallinarum to the lymph nodes, liver, and spleen, accompanied by ⬆️TH17 cells at these sites and production of anti-RNA #autoantibodies. “
Have you ever wondered how pathobionts contribute to autoimmunity? In this week's issue of Science Translational Medicine @science.org we elucidate the mechanism how E.gallinarum influences systemic immune responses and aggravates autoimmunity.. #ImmunoSky #Microbiome
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Translocating gut pathobiont Enterococcus gallinarum induces TH17 and IgG3 anti-RNA–directed autoimmunity in mouse and human
Translocating pathobiont Enterococcus gallinarum promotes human TH17 and anti-RNA IgG3 autoantibody responses in patients with autoimmune disease.
www.science.org
February 8, 2025 at 8:43 PM
Have you ever wondered how pathobionts contribute to autoimmunity? In this week's issue of Science Translational Medicine @science.org we elucidate the mechanism how E.gallinarum influences systemic immune responses and aggravates autoimmunity.. #ImmunoSky #Microbiome
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...