Sophia Mädler
@sophia-maedler.bsky.social
PostDoc @mpibiochem.bsky.social in @mannlab.bsky.social | PhD in Biochemistry | Developer of scPortrait & SPARCS | DL-driven representation learning for single-cell image analysis
https://sophia-maedler.com
https://sophia-maedler.com
Reposted by Sophia Mädler
🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights.
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
September 28, 2025 at 5:50 PM
🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights.
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
So glad to see scportrait finally out on
@biorxivpreprint.bsky.social ❤️
Check out the tweetorial about our main findings 👇
It was a pleasure working with everyone who contributed to this project.
@biorxivpreprint.bsky.social ❤️
Check out the tweetorial about our main findings 👇
It was a pleasure working with everyone who contributed to this project.
1/
Tomorrow’s large scale cross-modality models will further unlock biology, but they need standardized inputs. With @sophia-maedler.bsky.social & @nik-as.bsky.social, we built #scPortrait, @scverse.bsky.social package to turn microscopy images into single-cell image datasets for multimodal modeling
Tomorrow’s large scale cross-modality models will further unlock biology, but they need standardized inputs. With @sophia-maedler.bsky.social & @nik-as.bsky.social, we built #scPortrait, @scverse.bsky.social package to turn microscopy images into single-cell image datasets for multimodal modeling
September 24, 2025 at 1:08 PM
So glad to see scportrait finally out on
@biorxivpreprint.bsky.social ❤️
Check out the tweetorial about our main findings 👇
It was a pleasure working with everyone who contributed to this project.
@biorxivpreprint.bsky.social ❤️
Check out the tweetorial about our main findings 👇
It was a pleasure working with everyone who contributed to this project.
Reposted by Sophia Mädler
Our preprint on scPortrait is out! We built a framework + format to turn microscopy into standardized single-cell image datasets. #scPortrait scales >100M cells, integrates with @scverse.bsky.social, & enables cross-modality modeling from morphology to transcriptomics
doi.org/10.1101/2025...
doi.org/10.1101/2025...
scPortrait integrates single-cell images into multimodal modeling
Machine learning increasingly uncovers rules of biology directly from data, enabled by large, standardized datasets. Microscopy images provide rich information on cellular architecture and are accessi...
doi.org
September 24, 2025 at 12:22 PM
Our preprint on scPortrait is out! We built a framework + format to turn microscopy into standardized single-cell image datasets. #scPortrait scales >100M cells, integrates with @scverse.bsky.social, & enables cross-modality modeling from morphology to transcriptomics
doi.org/10.1101/2025...
doi.org/10.1101/2025...