Sofie Seghers
sofieseghers.bsky.social
Sofie Seghers
@sofieseghers.bsky.social
Medical Oncologist in training 👩🏼‍⚕️
Cancer researcher 🧫🔬
🧬How much does media choice alter tumor organoids?
Our new preprint compares OncoPro vs Wnt-based formulations, revealing distinct phenotype & drug response landscapes in PDOs, critical for translational screens.

www.biorxiv.org/content/10.6...
Comparative characterization of OncoPro and Wnt-Based media reveals distinct phenotypic and pharmacologic states in patient-derived tumor organoids
Background: Patient-derived tumor organoids (PDTOs) are strongly influenced by culture medium. We compared OncoPro (OP) Tumoroid Culture medium with conventional Wnt/R-spondin medium (Wnt). This recen...
www.biorxiv.org
December 16, 2025 at 7:20 PM