Smolka Lab
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smolka-lab.bsky.social
Smolka Lab
@smolka-lab.bsky.social
Signaling mechanisms in genome biology: DNA repair, DNA replication and the cell cycle. Proteomic tools for exploring kinases and phosphatases.
Cornell University, Ithaca - https://smolka.wicmb.cornell.edu
Check out our new biosensor technology to study DDR kinase signaling: ProKAS.

We combine:
-proteomics
-engineered peptide sensors
-a new concept of amino acid barcodes

ProKAS tracks kinase signaling with spatial resolution and produces highly quantitative data.

Just published today: rdcu.be/ePNo0
November 13, 2025 at 6:22 PM
Excited to share our preprint reporting a completely new approach to study kinase signaling: ProKAS.

ProKAS is based on a tandem array of peptide sensors with barcodes for multiplexed, spatial and kinetic applications.

We applied it to DDR kinases. Please share.

www.biorxiv.org/content/10.1...
December 17, 2024 at 2:10 PM