Lange lab @ Aarhus University/SDCA/UC San Diego
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slangelab.bsky.social
Lange lab @ Aarhus University/SDCA/UC San Diego
@slangelab.bsky.social
Dad and Scientist, working to understand #muscle #development and #diseases (#myopathies, #heart #failure) at Aarhus University and Steno Diabetes Center Aarhus, Denmark & UC San Diego, US. Opinions are my own.
Website: slangelab.org
Our highlight on "Novel links of ATG4 proteases to cytoskeletal adapters of the obscurin protein family"
that summarizes work by Virginia Actis Dato & Kyohei Fujita is now available @tandfresearch.bsky.social

#autophagy #mitophagy #atg4 #obscurin #obsl1

www.tandfonline.com/doi/full/10....
October 16, 2025 at 6:20 AM
We have something new 'cooking'. Our collaboration with @hesselanthony.bsky.social and his team @ambiotech.us saw 'first light' for some of our muscle samples @brookhavenlab.bsky.social NSLS II beamline. Looking forward to some cool small angle X-ray fiber diffraction patterns...
June 28, 2025 at 6:29 PM
Congratulations to Rob Johnson (postdoc @au.dk), who received a poster award at this years International Society for heart research #ISHR meeting in Nara, Japan, for his poster presentation on the Ankrd1 signaling pathway in #dilated_cardiomyopathy #DCM.
May 16, 2025 at 11:17 PM
Great to run into Kyohei, who is now Assist. Prof. in Tokyo. Here is the whole team attending the #ISHR2025 conference in Nara, Japan.
May 13, 2025 at 6:40 AM
May 13, 2025 at 6:37 AM
More impressions
May 13, 2025 at 6:37 AM
Lena an Rob from the lab are hard at work during this years #ISHR world meeting in Nara.
May 13, 2025 at 4:10 AM
It was great to welcome Prof. Farah Sheikh from @ucsandiego.bsky.social to @au.dk for the 1st Intl. Guest Lecture of the #Cardiovascular #PhD #programme and hear about her fantastic work on #arrhythmogenic #cardiomyopathy that successfully takes scientific findings to #clinicaltrial.
March 27, 2025 at 10:12 AM
New paper alert. 🚨
We finally published our manuscript describing that "Combined Loss of Obsc and Obsl1 in Murine Hearts Results in Diastolic Dysfunction, Altered Metabolism, and Deregulated Mitophagy"
Find it at @ahajournals.bsky.social #CirculationHF

Link: www.ahajournals.org/doi/10.1161/...
March 11, 2025 at 7:00 PM
We had a great visit to the lab of Prof. Katja Gehmlich @ Birmingham University to learn about engineered heart tissues using #iPSC-derived #cardiomyocytes. A big thank you to the support by the #DanishCardiovascularAcademy #DCA
March 11, 2025 at 12:21 PM
Great to attend the 2025 Winter Meeting of the Danish #Cardiovascular Academy and contribute with Christian Aalkjær & Emma Börgeson to the Grant writing Workshop. I hope all participants learnt something useful.
dcacademy.dk/winter-meeting
March 2, 2025 at 5:49 AM