We are pleased to welcome Dr. Olivier Ayrault from Institut Curie as a guest speaker for the CENOS-NBTP seminar series presenting "Causal Multi-omics Integration Reveals Metabolic Dependencies in Human Medulloblastoma".

A new computational method to separate bulk multi-omics data has been developed in collaboration between Qian Li and Paul Northcott’s lab. MOADE can predict cell types and generate personalized molecular profiles for analyzing complex tissues and tumors. (1/2)

Alisha Kardian, graduate student in the Mack lab, is the 2025 recipient for the prestigious Schweisguth Prize awarded for the best scientific article by a trainee in pediatric oncology. Congratulations on this outstanding achievement! siop-online.org/schweisguth-...

Congratulations to co-first authors Dr. Amir Arabzade and Srinidhi Varadharajan, Dr. Stephan Mack in DNB/CENOS, and Dr. Richard Kriwacki in Structural Biology on the publication of your work!

The Mack lab congratulates Amelia Hancock, a student from the ‪@uniofbath.bsky.social‬ exchange program, for her fantastic presentation on the work conducted during her year-long rotation. She has been an awesome part of the lab and will be greatly missed!

Dr. Stephen Mack, Associate Member of DNB & CENOS, is presenting “Deciphering the molecular and cellular basis of fusion driven ependymoma to uncover novel therapies” for the virtual Science of Childhood Cancer Lecture Aug 21. stjude.org/socc

The Baker lab had a fantastic experience mentoring POE intern Ethan Wunibald through the summer. He did an excellent job learning an array of techniques in the lab and presenting his findings. We look forward to seeing what he accomplishes next!

The Northcott lab is proud of High School Research Immersion Program student Catherine Carney for her summer research project poster. Your hard work and boundless curiosity was clear in your findings and way you answered tough questions. We know you have a bright future ahead!

Congratulations to the Northcott lab for 10 years at St Jude! Thank you to the Mack lab for joining as we celebrate this important milestone!

We are pleased to welcome Dr. Sameer Agnihotri from the University of Pittsburgh as a guest speaker for the CENOS-NBTP seminar series presenting "Microenvironmental, Epitranscriptomic, and Chromosomal Engineering Approaches to Uncover Translational Targets for Gliomas".

We are pleased to welcome Dr. Alex Miller from NYU Langone Health and Perlmutter Cancer Center as a guest speaker for the CENOS-NBTP seminar series presenting "Tapping the Genome: Liquid biopsies for CNS tumors".

Read about Tuyu’s project “Functional characterization of tumor neuronal networks that drive ependymoma” to understand how tumor and surrounding cells interact to change tumor growth and brain function tinyurl.com/5y5pd6sc

The proteosome fine-tunes protein levels; defects in targeted degradation cause disease, such as mutations in KBTBD4 driving medulloblastoma. Investigators at UW, Harvard, and St. Jude identified these mutations create interactions with new protein targets to aberrantly degrade them.

Congratulations to Dr. Stephanie Wu! Her poster on organoid models for medulloblastoma received the exceptional poster award at the Annual Comprehensive Cancer Center Postdoctoral Symposium.

The Science of Childhood Cancer is an interactive, weekly lecture series designed to engage the scientific community on key questions in pediatric cancer research. The Spring 2025 lecture season begins February 6 and runs through May 15. www.stjude.org/education-tr...

Today is #WorldCancerDay, and St. Jude is as committed as ever to fighting childhood cancer on all fronts. Danny Thomas said, “No child should die in the dawn of life.”

We are pleased to welcome Dr. Samuel McBrayer from UT Southwestern as a guest speaker for the CENOS-NBTP seminar series presenting "Metabolic control of neural cell fate and function."