Brain Injury Research Center (BIRC) of Mount Sinai
@sinaitbi.bsky.social
We conduct cutting-edge research, with a primary focus on addressing the challenges of living with TBI.
MRI data indicated that cognitive & mood/behavioral phenotypes were associated with reduced cortical volumes in specific brain networks compared to phenotype with few deficits which shows promising imaging biomarkers & intervention targets for chronic TBI
pmc.ncbi.nlm.nih.gov/articles/PMC12198765/
pmc.ncbi.nlm.nih.gov/articles/PMC12198765/
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global funct...
pmc.ncbi.nlm.nih.gov
July 2, 2025 at 3:00 PM
MRI data indicated that cognitive & mood/behavioral phenotypes were associated with reduced cortical volumes in specific brain networks compared to phenotype with few deficits which shows promising imaging biomarkers & intervention targets for chronic TBI
pmc.ncbi.nlm.nih.gov/articles/PMC12198765/
pmc.ncbi.nlm.nih.gov/articles/PMC12198765/
The 4 phenotypes were: 1) mixed cognitive and mood/behavioral deficits 2) predominant cognitive deficits 3) predominant mood/behavioral deficits 4) few deficits across domains. Phenotypes were based on 41 clinical measures and validated through advanced clustering methods.
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global funct...
pmc.ncbi.nlm.nih.gov
July 2, 2025 at 3:00 PM
The 4 phenotypes were: 1) mixed cognitive and mood/behavioral deficits 2) predominant cognitive deficits 3) predominant mood/behavioral deficits 4) few deficits across domains. Phenotypes were based on 41 clinical measures and validated through advanced clustering methods.