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How do hematopoietic stem cells resist inflammatory damage and do not age prematurely? Turns out that Semaphorin 4A-producing neutrophils come to rescue, as we report in our first paper, out in Nature Aging rdcu.be/d7UvQ. Cudos to 36 coauthors, reviewers and NA editorial staff!
Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells
Nature Aging - Toghani, Gupte et al. identify semaphorin 4A as a cell-extrinsic factor that protects myeloid-biased hematopoietic stem cells from inflammaging, mainly produced by their...
rdcu.be
February 7, 2025 at 7:51 AM
How do hematopoietic stem cells resist inflammatory damage and do not age prematurely? Turns out that Semaphorin 4A-producing neutrophils come to rescue, as we report in our first paper, out in Nature Aging rdcu.be/d7UvQ. Cudos to 36 coauthors, reviewers and NA editorial staff!