Shyamal
shyamalm.bsky.social
Shyamal
@shyamalm.bsky.social
Assistant Professor | U Mich
While tau adopts PHF/SF folds as expected in Alzheimer's, the CTE-fold might be a common occurrence in pathologies with TDP-43 aggregation. The exact molecular mechanisms that drive this remain to be investigated.
October 23, 2025 at 11:21 AM
This work was singlehandedly spearheaded by a graduate student in the lab, Renaldo Sutanto.
Link to the paper: www.biorxiv.org/content/10.1...

Comments and thoughts, welcome!
In situ cryo-ET redefines HPV disassembly and transport paradigms
Human papillomavirus (HPV) causes 4.5% of all human cancers, although a complete cellular basis of infection remains unclear. The mechanisms of virus disassembly and transport are particularly enigmat...
www.biorxiv.org
September 7, 2025 at 11:41 AM