Our team did something pretty magical to deliver the haplotype-resolved view of those medically relevant and paralogous genes. Btw, this is completely de novo, without using any population prior knowledge on known haplotypes.

If you are interested in segmental duplications, I'm happy to chat.

1% for the first question. Details on extraction will be shared later! :)

The template size at 99th percentile from HMW extraction is typically 100-300kb with some greater than 300kb. Full details will be publicly shared later.

Yes, one could design a de novo assembly process that takes advantage of the templates. The algorithm side of this technology is super fun :)

Full details on the prep and computational process will be shared later, stay tuned :)

iphone 15 main camera! :)

Feel free to add me :)