SHORTEN-2 trial
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shorten2trial.bsky.social
SHORTEN-2 trial
@shorten2trial.bsky.social
RCT 7 vs 14 days of treatment for P. aeruginosa BSI.
Updated trial progress and #FOAMed on P. aeruginosa.
#AMSSky #IDSky #PsWatch
Powered by @guiaprioam.bsky.social

📚 Full protocol: https://shorturl.at/xN0wj
🌐 https://clinicaltrials.gov/study/NCT05210439
Recruitment for SHORTEN-2 is officially complete!
Our team is now wrapping up follow-up and polishing databases. Hope to have results ready in the first half of 2026!

Hats off to this awesome research team! 🥳
#AMSsky #IDsky @seimc.bsky.social @ciberisciii.bsky.social @ibis-investigacion.bsky.social
October 18, 2025 at 9:57 AM
This metaanalysis of observational studies in SOT suggests that non-complicated graft infections could be treated 7d, and yet transplant patients have been excluded from most RCT on duration.

Time for a #ShorterIsBetter RCT in #TxID!

kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F... #IDsky #AMSsky
July 4, 2025 at 10:44 PM
Today we celebrated our 3rd Annual Researchers’ Meeting at the XXVIII Congress of @seimc.bsky.social!

Only 2️⃣4️⃣ patients left to complete the trial!

An amazing team doing an amazing work! 🤩🔝

#IDSky #AMSsky #TeamPride
May 23, 2025 at 4:49 PM
Only 58 patients to go!
Recruitment is moving along as planned, and fingers crossed, we’ll be done before summer.
Huge shoutout to the @shorten2trial.bsky.social team for keeping up the great work!
#AMSsky #IDSky #ShorterIsBetter
December 2, 2024 at 5:34 PM
Despite our growing antibiotic arsenal, non-fermenting GNB frequently keep leaving us without therapeutic options.

This article explores the present and the future of therapies against DTR NF-GNB: journals.lww.com/co-infectiou...

#PsWatch #AMSsky #IDsky
November 25, 2024 at 9:48 PM
MDR-P. aeruginosa is usually underrepresented in studies on treatment duration, including the former meta-analysis.

In this later study on HAP/VAP by MDR-PsA, no improved outcomes were observed with treatments >8d either:
📚 bmcinfectdis.biomedcentral.com/articles/10....

#PsWatch #AMSsky #IDSky
November 24, 2024 at 4:30 PM
What's the best duration for treating uncomplicated P. aeruginosa-BSI?

This metaanalysis of observational studies (n=1746)
found no differences in recurrence+mortality for short (<10d) compared to prolonged treatments.

📖 www.journalofhospitalinfection.com/article/S019...

#PsWatch #AMSsky #IDsky
November 24, 2024 at 4:11 PM
Our @shorten2trial.bsky.social aims to confirm that 7-day treatments are superior to 14-day courses for uncomplicated P. aeruginosa BSI.
Check out our full protocol 👉🏻 journals.plos.org/plosone/arti...
#AMSsky #IDSky
November 21, 2024 at 8:07 AM