Samuel Haysom
@shaysom.bsky.social
Structural biologist at Nxera Pharma | CryoEM | drug discovery | GPCRs | in silico protein design
Reposted by Samuel Haysom
See our latest paper on BAM action. Great work to the team and super collaborations with @naranson.bsky.social @antoncalabrese.bsky.social and @Jean Francois collet. Have a read rdcu.be/eJjDp
Molecular insights into how the motions of the β-barrel and POTRA domains of BamA are coupled for efficient function
Nature Communications - BamA is the catalytic core of the BAM complex, which inserts proteins into bacterial outer membranes. Here, the authors show that hinge flexibility between BamA’s...
rdcu.be
October 4, 2025 at 9:32 AM
See our latest paper on BAM action. Great work to the team and super collaborations with @naranson.bsky.social @antoncalabrese.bsky.social and @Jean Francois collet. Have a read rdcu.be/eJjDp
Reposted by Samuel Haysom
Berks and @smlea.bsky.social labs also found yet a different BAM architecture in Flavobacterium johnsoniae, another member of Bacteroidota.
doi.org/10.1038/s415...
doi.org/10.1038/s415...
A new paradigm for outer membrane protein biogenesis in the Bacteroidota - Nature
Structural and biochemical studies of the β-barrel-assembly machinery from Flavobacterium johnsoniae reveal a subunit composition and assembly that are distinct from those of the canonical Escherichia coli complex.
doi.org
October 2, 2025 at 6:20 AM
Berks and @smlea.bsky.social labs also found yet a different BAM architecture in Flavobacterium johnsoniae, another member of Bacteroidota.
doi.org/10.1038/s415...
doi.org/10.1038/s415...