Sharok Shekarriz
sharok.bsky.social
Sharok Shekarriz
@sharok.bsky.social
Reposted by Sharok Shekarriz
Publication alert: "No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations" ‪@natcomms.nature.com‬ The backstory is particularly interesting-it's a tale of the conflicting needs of scientists & decision makers in times of disinformation ....1/n
No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations
Nature Communications - Repeated vaccination is needed to maintain high levels of SARS-CoV-2 immunity in vulnerable populations, but there is concern that it could lead to immune exhaustion. Here,...
rdcu.be
June 6, 2025 at 7:04 PM
Reposted by Sharok Shekarriz
Its such a privilege to be part of this work. It’s been years in the making but only because of how thorough and conscientious @sharok.bsky.social , @surettem.bsky.social and other co-authors have been to make sure we got this right.

Huge congrats, Sharok, on this amazing study 🎉
April 25, 2025 at 6:09 PM
A lot of what looks like microbial engraftment after FMT might actually be noise. Using placebo sequencing and culture-enriched metagenomics, we sort signal from noise. Our latest from the Surette lab: www.nature.com/articles/s41... @surettem.bsky.social @mcmasteruniversity.bsky.social
Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise - Nature Communications
Here, the authors profile bacterial engraftment in UC patients receiving FMT from a single donor and placebo samples to estimate noise, showing a significant level of false-positive engraftment, which...
www.nature.com
April 25, 2025 at 3:22 PM