Sharan Janjuha
@sharan-janjuha.bsky.social
Gene editing | Spatial-omics | Molecular medicine.
Post-doc with Schwank Lab, UZH Zurich. PhD from CRTD, Dresden.
Post-doc with Schwank Lab, UZH Zurich. PhD from CRTD, Dresden.
Ever wondered how you could visualise you base or prime edited cells? Here, we applied in situ sequencing to spatially resolve base and prime editing outcomes in mice and macaque tissues!
Grateful to all the co-authors for their wonderful contributions! 🙂
Full text: www.nature.com/articles/s41...
Grateful to all the co-authors for their wonderful contributions! 🙂
Full text: www.nature.com/articles/s41...
Spatial profiling of gene editing by in situ sequencing in mice and macaques
Nature Biomedical Engineering - Targeted in situ sequencing directly maps editing rates at single-cell resolution in postmortem tissues to visualize base and prime editor delivery.
www.nature.com
September 19, 2025 at 6:52 PM
Ever wondered how you could visualise you base or prime edited cells? Here, we applied in situ sequencing to spatially resolve base and prime editing outcomes in mice and macaque tissues!
Grateful to all the co-authors for their wonderful contributions! 🙂
Full text: www.nature.com/articles/s41...
Grateful to all the co-authors for their wonderful contributions! 🙂
Full text: www.nature.com/articles/s41...