Shane E. Ridoux
@shaneridoux.bsky.social
Genetic epidemiologist-in-training | PhD student @ ColoradoSPH
Mapping gene-gene interactions in autoimmune disease
Networks, information theory, and public science
Mapping gene-gene interactions in autoimmune disease
Networks, information theory, and public science
The concept of genetic drift didn’t quite click at first… so I built a simulation to help myself understand it better.
If you’ve ever wondered how random chance can shape the genetic makeup of populations, this might help it click for you too. shaneridoux.github.io/posts/2025/0...
If you’ve ever wondered how random chance can shape the genetic makeup of populations, this might help it click for you too. shaneridoux.github.io/posts/2025/0...
What is Genetic Drift?
Sometimes, chance alone can change the fate of genes in a population.Read more
shaneridoux.github.io
July 26, 2025 at 5:01 AM
The concept of genetic drift didn’t quite click at first… so I built a simulation to help myself understand it better.
If you’ve ever wondered how random chance can shape the genetic makeup of populations, this might help it click for you too. shaneridoux.github.io/posts/2025/0...
If you’ve ever wondered how random chance can shape the genetic makeup of populations, this might help it click for you too. shaneridoux.github.io/posts/2025/0...
As I wrap up my day, I am reminded of the “joys” 🙄 of quality control (QC)
Hardy-Weinberg Equilibrium (HWE) assumes random mating and no confounding structure
👀 End-of-day Takeaway: Do HWE filtering in CONTROLS, stratified by known subpops (i.e. sex/ancestry)
Don’t let QC throw out real biology!
Hardy-Weinberg Equilibrium (HWE) assumes random mating and no confounding structure
👀 End-of-day Takeaway: Do HWE filtering in CONTROLS, stratified by known subpops (i.e. sex/ancestry)
Don’t let QC throw out real biology!
July 15, 2025 at 1:32 AM
As I wrap up my day, I am reminded of the “joys” 🙄 of quality control (QC)
Hardy-Weinberg Equilibrium (HWE) assumes random mating and no confounding structure
👀 End-of-day Takeaway: Do HWE filtering in CONTROLS, stratified by known subpops (i.e. sex/ancestry)
Don’t let QC throw out real biology!
Hardy-Weinberg Equilibrium (HWE) assumes random mating and no confounding structure
👀 End-of-day Takeaway: Do HWE filtering in CONTROLS, stratified by known subpops (i.e. sex/ancestry)
Don’t let QC throw out real biology!
Reflecting on today… there has to be a better protocol for quality control in genetic association studies. Particularly when uncovering interactions is the goal. Anyone know of any good references to check out?
June 13, 2025 at 4:00 AM
Reflecting on today… there has to be a better protocol for quality control in genetic association studies. Particularly when uncovering interactions is the goal. Anyone know of any good references to check out?
As a scientist (in-training), I can't help but be excited and intimidated by the task of open and public scientific communication. While it is something I consider my duty, it is something I have never been quite good at.
Consider this a start? Any opinions from folks?
Consider this a start? Any opinions from folks?
June 6, 2025 at 7:33 PM
As a scientist (in-training), I can't help but be excited and intimidated by the task of open and public scientific communication. While it is something I consider my duty, it is something I have never been quite good at.
Consider this a start? Any opinions from folks?
Consider this a start? Any opinions from folks?