Sara Formichetti
sformich.bsky.social
Sara Formichetti
@sformich.bsky.social
Curious of how DNA works in space & time, evolution & development.
Postdoc in @thomasgregor.bsky.social Lab, @pasteur.fr , Paris.
PhD at @embl.org .
Dancer & singer every time I can.
A few weeks of delay but still very fresh, the end of an unforgettable chapter: my main PhD paper is in PNAS!!! 🤩 1/5
www.pnas.org/doi/10.1073/...
Perturbing nuclear glycosylation in the mouse preimplantation embryo slows down embryonic development | PNAS
The main form of intracellular protein glycosylation (O-GlcNAc) is reversible and has been mapped on thousands of cytoplasmic and nuclear proteins,...
www.pnas.org
May 5, 2025 at 6:40 PM
We were so many. Too special to see all Parisian researchers together...our work is power and together we are powerful!!! #StandUpForScience #StandUpForScienceFrance
@pasteur.fr & its Direction present!!!
@standupforscience.bsky.social @standupforscifr.bsky.social @sufs-paris-rp.bsky.social
March 9, 2025 at 9:52 AM
1st 1st-author paper of my PhD (& of my career 😊) is out 🤓 OGT is the only enzyme for reversible intracellular glycosylation in animals. Using a mouse allelic series of hypomorphic OGT-mutants, we discover that intracellular glycosylation is essential for mammalian embryonic development..1/3
embl.org EMBL @embl.org · Jan 10
Researchers in the Boulard group at EMBL Rome demonstrated for the first time that the catalytic activity of the OGT enzyme is essential for embryonic development, and that when it’s reduced, embryo development is delayed – especially in males.

www.embl.org/news/science...

🧪@sformich.bsky.social
Sweet gene regulation in the mammalian embryo | EMBL
Researchers in the Boulard group at EMBL Rome demonstrated for the first time that the catalytic activity of the OGT enzyme is essential for embryonic development.
www.embl.org
January 11, 2025 at 5:12 PM