Melissa Wilson
@sexchrlab.bsky.social
Geneticist. Parent. Studying sex chromosomes and sex as a biological variable in disease.
Posts and opinions are my own.
Posts and opinions are my own.
Reposted by Melissa Wilson
With a nice feature in ASU news! news.asu.edu/20250918-sci...
Scientists discover genetic adaptations can help those living in dry climates | ASU News
A team of international scientists has uncovered key genetic adaptations underlying survival in hot and dry environments, revealing how natural selection may have enabled some pastoralist populations ...
news.asu.edu
September 20, 2025 at 12:04 AM
With a nice feature in ASU news! news.asu.edu/20250918-sci...
Some animals are more equal than others.
July 30, 2025 at 12:34 PM
Some animals are more equal than others.
Ooh, I love to hear it!
July 14, 2025 at 11:19 PM
Ooh, I love to hear it!
Ooh, that's cool.
Is there a ref genome for the species?
Idk genome size, but if possible to generate long reads for the parents (not necessarily assemblies, but the cost has come down a lot) you can try to phase so you will have some haplotypes information to help with imputation of linked SNPs.
Is there a ref genome for the species?
Idk genome size, but if possible to generate long reads for the parents (not necessarily assemblies, but the cost has come down a lot) you can try to phase so you will have some haplotypes information to help with imputation of linked SNPs.
July 14, 2025 at 6:35 PM
Ooh, that's cool.
Is there a ref genome for the species?
Idk genome size, but if possible to generate long reads for the parents (not necessarily assemblies, but the cost has come down a lot) you can try to phase so you will have some haplotypes information to help with imputation of linked SNPs.
Is there a ref genome for the species?
Idk genome size, but if possible to generate long reads for the parents (not necessarily assemblies, but the cost has come down a lot) you can try to phase so you will have some haplotypes information to help with imputation of linked SNPs.
Are the grandparents all inbred (homozygous at all/nearly all loci)?
I'm generally always more in favor of WGS over Radseq due to more even coverage across individuals, but curious what arguments there are in the opposite direction.
I'm generally always more in favor of WGS over Radseq due to more even coverage across individuals, but curious what arguments there are in the opposite direction.
July 14, 2025 at 6:19 PM
Are the grandparents all inbred (homozygous at all/nearly all loci)?
I'm generally always more in favor of WGS over Radseq due to more even coverage across individuals, but curious what arguments there are in the opposite direction.
I'm generally always more in favor of WGS over Radseq due to more even coverage across individuals, but curious what arguments there are in the opposite direction.
Yes, I realized I responded thinking of a mouse model but the species and genetic background make a big difference.
July 14, 2025 at 6:16 PM
Yes, I realized I responded thinking of a mouse model but the species and genetic background make a big difference.
Highly recommend the wgs over radseq for more comparable sequence across individuals. Depending on the known parental genotypes, the imputation would work very well. Is this in mice with known parental genome sequences?
July 14, 2025 at 6:15 PM
Highly recommend the wgs over radseq for more comparable sequence across individuals. Depending on the known parental genotypes, the imputation would work very well. Is this in mice with known parental genome sequences?