Serena Orr, MD, MSc
@serenaorr.bsky.social
Pediatric neurologist & headache specialist | Associate professor @UCalgaryMed | Researcher @UofCr4kids @HotchkissBrain www.pehrl.ca | Associate editor @HeadacheJournal
#Migraine remains the #top cause of #neurological #disability in #children and #adolescents in the 2025 GBD neurological diseases publication @jama.com: jamanetwork.com/journals/jam...
US Burden of Disorders Affecting the Nervous System
This cross-sectional study analyzes data from the Global Burden of Disease 2021 study to quantify aggregated health loss from diseases affecting the nervous system in the United States.
jamanetwork.com
November 26, 2025 at 8:45 PM
#Migraine remains the #top cause of #neurological #disability in #children and #adolescents in the 2025 GBD neurological diseases publication @jama.com: jamanetwork.com/journals/jam...
Hot off the press: Our work on #Chinook #winds and #migraine attack onset in #children and #adolescents with surprising null findings @ahsheadache.bsky.social @headachejournal.bsky.social : headachejournal.onlinelibrary.wiley.com/doi/10.1111/...
<em>Headache: The Journal of Head and Face Pain</em> | AHS Journal | Wiley Online Library
Objective To explore the relationship between migraine attack onset in children and adolescents and Chinooks, which are dry and warm westerly winds that generally occur in the winter and bring about...
headachejournal.onlinelibrary.wiley.com
November 5, 2025 at 2:43 PM
Hot off the press: Our work on #Chinook #winds and #migraine attack onset in #children and #adolescents with surprising null findings @ahsheadache.bsky.social @headachejournal.bsky.social : headachejournal.onlinelibrary.wiley.com/doi/10.1111/...
November 4, 2025 at 4:11 PM
What a week - Honored to be a #Top40 and our paper on #migraine and #trauma informed care was published.
Top 40: www.avenuecalgary.com/top-40-under...
Migraine and trauma-informed care: link.springer.com/epdf/10.1007...
Top 40: www.avenuecalgary.com/top-40-under...
Migraine and trauma-informed care: link.springer.com/epdf/10.1007...
Serena L. Orr | Top 40 Under 40 2025 - Avenue Calgary
Serena Orr is changing the way health-care providers view and treat headache disorders.
www.avenuecalgary.com
October 30, 2025 at 6:48 PM
What a week - Honored to be a #Top40 and our paper on #migraine and #trauma informed care was published.
Top 40: www.avenuecalgary.com/top-40-under...
Migraine and trauma-informed care: link.springer.com/epdf/10.1007...
Top 40: www.avenuecalgary.com/top-40-under...
Migraine and trauma-informed care: link.springer.com/epdf/10.1007...
Interesting data: Dual therapy with #anti-CGRP medications and #OnabotulinumtoxinA resulted in reduced #EmergencyDepartment visits compared to monotherapy with either of these in #adults with #migraine www.neurology.org/doi/pdf/10.1...
Neurology® Journals
www.neurology.org
October 8, 2025 at 4:53 PM
Interesting data: Dual therapy with #anti-CGRP medications and #OnabotulinumtoxinA resulted in reduced #EmergencyDepartment visits compared to monotherapy with either of these in #adults with #migraine www.neurology.org/doi/pdf/10.1...
Glad to see the American Academy of Neurology respond swiftly to the HHS’ claim linking #autism to prenatal acetaminophen exposure: www.aan.com/siteassets/h...
www.aan.com
September 23, 2025 at 1:34 AM
Glad to see the American Academy of Neurology respond swiftly to the HHS’ claim linking #autism to prenatal acetaminophen exposure: www.aan.com/siteassets/h...
Fabulous time in São Paulo sharing #migraine #science, #clinical pearls, and working on international #collaborations with my wonderful colleagues #InternationalHeadacheCongress
September 14, 2025 at 12:11 PM
Fabulous time in São Paulo sharing #migraine #science, #clinical pearls, and working on international #collaborations with my wonderful colleagues #InternationalHeadacheCongress
“Pain metamorphosis” - striking art at the #InternationalHeadacheCongress in #SãoPaulo
September 11, 2025 at 4:25 PM
“Pain metamorphosis” - striking art at the #InternationalHeadacheCongress in #SãoPaulo
Headed down to #SãoPaulo for the #InternationalHeadacheCongress meeting. Excited to share our recent work on #chinooks and #migraine attack onset in #children and #adolescents and to lecture on #non-pharmacologic treatments.
September 9, 2025 at 8:16 PM
Headed down to #SãoPaulo for the #InternationalHeadacheCongress meeting. Excited to share our recent work on #chinooks and #migraine attack onset in #children and #adolescents and to lecture on #non-pharmacologic treatments.
Check out our latest work showing that #pain #magnification (perceiving pain as #threat) is strongly associated with more #migraine related #disability at follow-up in youth with migraine @ahsheadache.bsky.social @headachejournal.bsky.social: headachejournal.onlinelibrary.wiley.com/doi/10.1111/...
<em>Headache: The Journal of Head and Face Pain</em> | AHS Journal | Wiley Online Library
Pain catastrophizing is a term that describes a person's tendency to magnify (i.e., to feel threatened) by pain, to ruminate (i.e., to think a lot) about pain, and to feel helpless about pain. We exa...
headachejournal.onlinelibrary.wiley.com
September 2, 2025 at 4:32 PM
Check out our latest work showing that #pain #magnification (perceiving pain as #threat) is strongly associated with more #migraine related #disability at follow-up in youth with migraine @ahsheadache.bsky.social @headachejournal.bsky.social: headachejournal.onlinelibrary.wiley.com/doi/10.1111/...
FDA has approved #fremanezumab for #migraine #prevention in #children and #adolescents with #episodic #migraine ir.tevapharm.com/news-and-eve...
FDA Approves Expanded Indication for AJOVY® (fremanezumab-vfrm), The First Anti-CGRP Preventive Treatment for Pediatric Episodic Migraine
FDA approves single-dose AJOVY ® (fremanezumab-vfrm) injection for the preventive treatment of episodic migraine in children and adolescents aged 6-17 who weigh 45 kilograms or more, offering a long-a...
ir.tevapharm.com
August 16, 2025 at 6:46 PM
FDA has approved #fremanezumab for #migraine #prevention in #children and #adolescents with #episodic #migraine ir.tevapharm.com/news-and-eve...
Reposted by Serena Orr, MD, MSc
Open Access:
A discrete-choice experiment survey in adults w episodic #migraine found, on average, respondents prefer an oral pill to injections or infusions, highlighting the importance of patient preference in choosing preventive treatments
headachejournal.onlinelibrary.wiley.com/share/BYXMW2...
A discrete-choice experiment survey in adults w episodic #migraine found, on average, respondents prefer an oral pill to injections or infusions, highlighting the importance of patient preference in choosing preventive treatments
headachejournal.onlinelibrary.wiley.com/share/BYXMW2...
June 25, 2025 at 1:30 AM
Open Access:
A discrete-choice experiment survey in adults w episodic #migraine found, on average, respondents prefer an oral pill to injections or infusions, highlighting the importance of patient preference in choosing preventive treatments
headachejournal.onlinelibrary.wiley.com/share/BYXMW2...
A discrete-choice experiment survey in adults w episodic #migraine found, on average, respondents prefer an oral pill to injections or infusions, highlighting the importance of patient preference in choosing preventive treatments
headachejournal.onlinelibrary.wiley.com/share/BYXMW2...
The #phase1 #pharmacokinetic #trial on the use of #eptinezumab in #children and #adolescents with #migraine is now published. Recommends weight-based dosing. @headachejournal.bsky.social headachejournal.onlinelibrary.wiley.com/doi/pdf/10.1...
<em>Headache: The Journal of Head and Face Pain</em> | AHS Journal | Wiley Online Library
There are limited treatment options to prevent migraine in young people (aged 6–17 years). Eptinezumab is proven to prevent migraine in adults, and in this open-label trial, we gave eptinezumab to yo...
headachejournal.onlinelibrary.wiley.com
June 6, 2025 at 8:36 PM
The #phase1 #pharmacokinetic #trial on the use of #eptinezumab in #children and #adolescents with #migraine is now published. Recommends weight-based dosing. @headachejournal.bsky.social headachejournal.onlinelibrary.wiley.com/doi/pdf/10.1...
Reposted by Serena Orr, MD, MSc
A woman took 5 hockey players to trial for alleged sexual assaults. She was subjected to 9 straight days of interrogation by 5 legal teams, one for each defendant. Our justice system is telling women they can't report multiple assaults or they will be victimized again.
www.cbc.ca/news/canada/...
www.cbc.ca/news/canada/...
RECAP | Woman’s testimony ends after 9 gruelling days of questions at world juniors sex assault trial | CBC
www.cbc.ca
May 15, 2025 at 2:28 AM
A woman took 5 hockey players to trial for alleged sexual assaults. She was subjected to 9 straight days of interrogation by 5 legal teams, one for each defendant. Our justice system is telling women they can't report multiple assaults or they will be victimized again.
www.cbc.ca/news/canada/...
www.cbc.ca/news/canada/...
Nothing to do with headache medicine but this is a great read 😊
NEWS: Marine crab survives epic hitch-hiking trip from Panama to Canmore in student's shoe
Marine crab survives epic hitch-hiking trip from Panama to Canmore in student's shoe
“While the species is not currently listed as invasive or controlled under Alberta legislation, FWES engaged with Environment Canada to ensure proper handling and assessment in accordance with federal and provincial protocols."
dlvr.it
May 9, 2025 at 4:00 AM
Nothing to do with headache medicine but this is a great read 😊
Fascinating results from UNITE trial showing that #fremanezumab reduces both #migraine days and #depressive symptoms in adults with #migraine and #depression - seminal trial first to look at treating both @jama.com: jamanetwork.com/journals/jam...
Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder
This randomized clinical trial investigates if treatment with fremanezumab compared with placebo leads to improvements in migraine and depressive symptoms in patients with migraine and comorbid major ...
jamanetwork.com
May 8, 2025 at 3:07 PM
Fascinating results from UNITE trial showing that #fremanezumab reduces both #migraine days and #depressive symptoms in adults with #migraine and #depression - seminal trial first to look at treating both @jama.com: jamanetwork.com/journals/jam...
Reposted by Serena Orr, MD, MSc
The little hat, the eye piece, the weird block suit. So quirky, so neuro
May 6, 2025 at 3:43 AM
The little hat, the eye piece, the weird block suit. So quirky, so neuro
The #CONSORT guidelines for #reporting the results of #RandomizedControlledTrials have been updated and published. See the new guidelines here: www.sciencedirect.com/science/arti...
CONSORT 2025 statement: updated guideline for reporting randomised trials
Well designed and properly executed randomised trials are considered the most reliable evidence on the benefits of healthcare interventions. However, …
www.sciencedirect.com
April 23, 2025 at 6:42 PM
The #CONSORT guidelines for #reporting the results of #RandomizedControlledTrials have been updated and published. See the new guidelines here: www.sciencedirect.com/science/arti...
I was invited by
@abhealthservices.bsky.social
to do a presentation for #youth and #families about #headaches and #migraine in #children and #adolescents and it is now posted on Youtube in case anyone is interested: www.youtube.com/watch?v=BHq-...
@abhealthservices.bsky.social
to do a presentation for #youth and #families about #headaches and #migraine in #children and #adolescents and it is now posted on Youtube in case anyone is interested: www.youtube.com/watch?v=BHq-...
Headache in kids and teens: Causes, treatment approach, and mental health (April 10, 2025)
YouTube video by Alberta Health Services
www.youtube.com
April 15, 2025 at 9:29 PM
I was invited by
@abhealthservices.bsky.social
to do a presentation for #youth and #families about #headaches and #migraine in #children and #adolescents and it is now posted on Youtube in case anyone is interested: www.youtube.com/watch?v=BHq-...
@abhealthservices.bsky.social
to do a presentation for #youth and #families about #headaches and #migraine in #children and #adolescents and it is now posted on Youtube in case anyone is interested: www.youtube.com/watch?v=BHq-...
Fascinating work using #MachineLearning to try and predict #incident #migraine cases in the HUNT study from #genetic and #clinical data. #Genetic data alone barely better than chance, but #clinical + #genetic data generated reasonable predictive accuracy: link.springer.com/article/10.1...
Prediction of new-onset migraine using clinical-genotypic data from the HUNT Study: a machine learning analysis - The Journal of Headache and Pain
Background Migraine is associated with a range of symptoms and comorbid disorders and has a strong genetic basis, but the currently identified risk loci only explain a small portion of the heritabilit...
link.springer.com
April 11, 2025 at 12:57 AM
Fascinating work using #MachineLearning to try and predict #incident #migraine cases in the HUNT study from #genetic and #clinical data. #Genetic data alone barely better than chance, but #clinical + #genetic data generated reasonable predictive accuracy: link.springer.com/article/10.1...
Reposted by Serena Orr, MD, MSc
There's no such thing as a self-made man or woman. No one succeeds without support.
"I did it on my own" is a sign of insecurity and entitlement. Acknowledging help is a mark of confidence and humility.
Giving credit to others doesn't undermine you. It elevates them.
"I did it on my own" is a sign of insecurity and entitlement. Acknowledging help is a mark of confidence and humility.
Giving credit to others doesn't undermine you. It elevates them.
April 5, 2025 at 8:19 PM
There's no such thing as a self-made man or woman. No one succeeds without support.
"I did it on my own" is a sign of insecurity and entitlement. Acknowledging help is a mark of confidence and humility.
Giving credit to others doesn't undermine you. It elevates them.
"I did it on my own" is a sign of insecurity and entitlement. Acknowledging help is a mark of confidence and humility.
Giving credit to others doesn't undermine you. It elevates them.
The #gender #WageGap for #neurologists is not improving @greenjournal.bsky.social: www.neurology.org/doi/10.1212/...
Gender Wage Gap Among Academic Neurologists | Neurology
ObjectivesDespite efforts to reduce the gender wage gap, a 2019 survey of American Academy of Neurology members showed that a significant gender wage gap was still evident. This study aims
to assess t...
www.neurology.org
March 26, 2025 at 2:11 PM
The #gender #WageGap for #neurologists is not improving @greenjournal.bsky.social: www.neurology.org/doi/10.1212/...
Back in my #hometown @Montreal for the International Brain Injury Association Congress, preparing my talk on #posttraumatic #headache in #children and #adolescents. Excited to connect with some #colleagues, #family, and #friends
March 19, 2025 at 2:10 PM
Back in my #hometown @Montreal for the International Brain Injury Association Congress, preparing my talk on #posttraumatic #headache in #children and #adolescents. Excited to connect with some #colleagues, #family, and #friends
My standout colleagues Drs. Noel & Birnie are looking to hire a #KnowledgeBroker to work on projects related to #pediatric #pain. Please consider and/or share! careers.ucalgary.ca/jobs/1579389...
Knowledge Broker to Improve Pain in Children and Families, Anaesthesia in
Calgary,
AB,
...
Knowledge Broker to Improve Pain in Children and Families, Anaesthesia in
Calgary,
AB,
...
careers.ucalgary.ca
March 17, 2025 at 3:23 PM
My standout colleagues Drs. Noel & Birnie are looking to hire a #KnowledgeBroker to work on projects related to #pediatric #pain. Please consider and/or share! careers.ucalgary.ca/jobs/1579389...