I carry all of you with me, in every challenge, in every victory. Because we are in this together, and together, we will go on.

We will go on.

Happy International Day of Women and Girls in Science.

#WomenInScience #WeBelong #StrongerTogether

It is these connections - the quiet nods of understanding, the fierce solidarity, the shared determination—that keep me going.

And then there are the allies. The ones who make space, who listen, who stand with us - not as saviors, but as partners in change.

There were and are always women beside me. Women who walk ahead and show me the way. Women who stand next to me, reminding me that we belong here. Women (and girls) who are just starting out but already carrying the fire.

9/ And finally,
@yogihooda.bsky.social, Arif Tanmoy & Team @chrfbd.bsky.social - incredible work in getting all of this together so quickly. Such a privilege working with you all & Prof Samir!

8/ As we celebrate holidays, let’s remember: surveillance is year-round work. Outbreaks like this highlight the critical need for vigilance, diagnostics, and public health action.

7/ Huge thanks to Popular Diagnostic Centre Ltd. and their incredible lab team for collecting, recording, and sending isolates. Surveillance saves lives, and this network is proof of that. 🙌

6/ Most patients recovered, but resistance data required shifting treatments.
This highlights the need for robust diagnostics, antimicrobial stewardship, and #typhoid conjugate #vaccines (#TCVs) to curb resistance.

5/ Genomic analysis links these strains to other countries in the region but with independent acquisition of resistance. No travel histories among patients suggest local transmission, emphasizing the need for ongoing surveillance.

4/ This lineage is NOT extensively drug-resistant (XDR). It remains susceptible to chloramphenicol & cotrimoxazole. However, 3rd generation cephalosporins is the most common empirical treatment in South Asia, so resistance to it poses a significant public health threat.

3/ We identified 47 cases of ceftriaxone-resistant typhoid. Of these, 17 were sequenced, revealing a new genotype-plasmid combo:
Genotype 4.3.1.2 carrying the blaCTX-M-15 gene on the pCROB1 plasmid—a novel lineage named 4.3.1.2.B1.