Jan Seebacher
@seebj.bsky.social
Proteomics Core Facility at Friedrich-Miescher Institute (FMI) Basel, @fmiscience.bsky.social.
#massspectrometry, #proteomics, #chemistry, #bioinformatics
#massspectrometry, #proteomics, #chemistry, #bioinformatics
Reposted by Jan Seebacher
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
September 8, 2025 at 8:15 AM
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Reposted by Jan Seebacher
Our cells pack DNA into tiny bundles that hide important parts. Researchers at the FMI and EPFL found this packing affects how the cancer-fighting protein p53 works, revealing new insights into cancer. www.fmi.ch/news-events/...
How DNA packaging controls the “genome’s guardian”
Our cells tightly pack DNA into structures called nucleosomes, which protect DNA but also hide important sites. The key cancer-fighting protein p53 can still access these hidden sites, especially at n...
www.fmi.ch
July 31, 2025 at 8:59 AM
Our cells pack DNA into tiny bundles that hide important parts. Researchers at the FMI and EPFL found this packing affects how the cancer-fighting protein p53 works, revealing new insights into cancer. www.fmi.ch/news-events/...
Reposted by Jan Seebacher
www.sciencedirect.com/science/arti...
I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬
Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌
I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬
Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌
A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin
Transcription factors (TFs) are key regulators of gene expression, yet many of their targets and modes of action remain unknown. In Schizosaccharomyce…
www.sciencedirect.com
February 26, 2025 at 4:41 PM
www.sciencedirect.com/science/arti...
I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬
Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌
I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬
Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌
Reposted by Jan Seebacher
We're hiring! Our IT Team is looking for a Linux Systems Engineer to support scientific computing and big data management. Apply here: www.fmi.ch/education-ca...
February 6, 2025 at 1:29 PM
We're hiring! Our IT Team is looking for a Linux Systems Engineer to support scientific computing and big data management. Apply here: www.fmi.ch/education-ca...
Reposted by Jan Seebacher
Want to follow some of our current members and alumni? Check out the FMI Starter Pack 👉https://bsky.app/start/did:plc:g3dn6h22ro42odcsxx5yxoq6/3lebsjhgpxl2c
January 22, 2025 at 7:17 AM
Want to follow some of our current members and alumni? Check out the FMI Starter Pack 👉https://bsky.app/start/did:plc:g3dn6h22ro42odcsxx5yxoq6/3lebsjhgpxl2c
Reposted by Jan Seebacher
Permanent position for a Linux Systems Engineer: Are you fond of scientific computing and/Linux/HPC and would enjoy working in a vibrant research environment? Have a look at our job opening: www.fmi.ch/education-ca...
Friedrich Miescher Institute, open position
Friedrich Miescher Institute, open position
www.fmi.ch
January 15, 2025 at 1:44 PM
Permanent position for a Linux Systems Engineer: Are you fond of scientific computing and/Linux/HPC and would enjoy working in a vibrant research environment? Have a look at our job opening: www.fmi.ch/education-ca...
Reposted by Jan Seebacher
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 16, 2024 at 11:50 AM
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
Reposted by Jan Seebacher
In a new study published in Nature Communications, researchers led by Guillaume Diss have provided key insights into how protein interactions are governed and how mutations influence cellular functions—work that might help advance personalized medicine.
Decoding protein interactions: A step toward personalized medicine
Investigating how proteins interact is key to understand how cells work and communicate. In a new study — the first of its kind to examine the effects of all possible mutations in a protein across int...
www.fmi.ch
December 3, 2024 at 8:37 AM
In a new study published in Nature Communications, researchers led by Guillaume Diss have provided key insights into how protein interactions are governed and how mutations influence cellular functions—work that might help advance personalized medicine.
Reposted by Jan Seebacher
Researchers in @labgrosshans.bsky.social & their collaborators developed a tool that maps how proteases—enzymes that process proteins—cut their targets. The work, published in Molecular Systems Biology, could revolutionize drug design for conditions like diabetes. www.fmi.ch/news-events/...
New tool to map protease specificity may pave the way for improved treatments
FMI researchers have developed a new tool that maps how proteases —enzymes that process proteins— cut their targets. This innovation offers new insight into the highly selective nature of proteases, w...
www.fmi.ch
November 28, 2024 at 8:45 AM
Researchers in @labgrosshans.bsky.social & their collaborators developed a tool that maps how proteases—enzymes that process proteins—cut their targets. The work, published in Molecular Systems Biology, could revolutionize drug design for conditions like diabetes. www.fmi.ch/news-events/...
Reposted by Jan Seebacher
For over 50 years, the FMI has proudly advanced biomedical research and training. As times evolve, so do we: we've joined Bluesky! Follow us for the latest updates and news about our institute 🌤️
November 26, 2024 at 9:20 AM
For over 50 years, the FMI has proudly advanced biomedical research and training. As times evolve, so do we: we've joined Bluesky! Follow us for the latest updates and news about our institute 🌤️
🔬 Join FMI! We’re seeking a proteomics expert to develop cutting-edge mass spectrometry applications. Collaborate with top researchers in Genome Regulation, Multicellular Systems, and Neurobiology.
Apply now or share this job ad in your network!
#proteomics #CoreFacility
www.fmi.ch/education-ca...
Friedrich Miescher Institute, open position
Friedrich Miescher Institute, open position
www.fmi.ch
November 20, 2024 at 1:23 PM
🔬 Join FMI! We’re seeking a proteomics expert to develop cutting-edge mass spectrometry applications. Collaborate with top researchers in Genome Regulation, Multicellular Systems, and Neurobiology.
Apply now or share this job ad in your network!
#proteomics #CoreFacility
www.fmi.ch/education-ca...