Séamus Holden 🔬🦠🧫
@seamusholden.bsky.social
Professor of Microbial Biophysics, University of Warwick. Interested in all things bacterial cell envelope, cell biophysics and advanced light microscopy. https://holdenlab.github.io/ Twitter (inactive): @seamus_holden
Further update - while looking for alternatives I found this new page on GraceBio's website gracebio.com/product/secu...
So it looks like they may have indeed recently started making them but just dont reply to my emails any more 😠😠
Not cheap ($115/25pk) but good to have a source.
So it looks like they may have indeed recently started making them but just dont reply to my emails any more 😠😠
Not cheap ($115/25pk) but good to have a source.
SecureSeal™ Frame - Grace Bio-Labs
SecureSeal™ Frame Only, 65ul, 15 X 16mm ID, 25 X 25mm OD, (Coverslips 620100, sold separately) - 25 PACK
gracebio.com
November 14, 2025 at 11:08 AM
Further update - while looking for alternatives I found this new page on GraceBio's website gracebio.com/product/secu...
So it looks like they may have indeed recently started making them but just dont reply to my emails any more 😠😠
Not cheap ($115/25pk) but good to have a source.
So it looks like they may have indeed recently started making them but just dont reply to my emails any more 😠😠
Not cheap ($115/25pk) but good to have a source.
Alternatively, a DIY solution might be possible. If anyone has any ideas on a suitable non-toxic double-sided adhesive sheet material, then purchasing those and using either consumer grade die-cutter or online-die cutting services could be a straightforward solution.
November 14, 2025 at 10:39 AM
Alternatively, a DIY solution might be possible. If anyone has any ideas on a suitable non-toxic double-sided adhesive sheet material, then purchasing those and using either consumer grade die-cutter or online-die cutting services could be a straightforward solution.
Unfortunately we are back to square one. @geobellward.bsky.social and @ivan-volkov.bsky.social had found iSpacers (www.sunjinlab.com/ispacer-sele...) looked promising, and custom sizes available so that seems like the next port of call
iSpacer selection guide – SUNJIN LAB
www.sunjinlab.com
November 14, 2025 at 10:39 AM
Unfortunately we are back to square one. @geobellward.bsky.social and @ivan-volkov.bsky.social had found iSpacers (www.sunjinlab.com/ispacer-sele...) looked promising, and custom sizes available so that seems like the next port of call
We have to assume at this point they will not make them and need to find alternative. Only last thing to check is if many others email techsupport@gracebio.com to ask about GeneFrame replacements it might motivate them? Could also be a US/non-US thing? Not great but worth trying.
November 14, 2025 at 10:39 AM
We have to assume at this point they will not make them and need to find alternative. Only last thing to check is if many others email techsupport@gracebio.com to ask about GeneFrame replacements it might motivate them? Could also be a US/non-US thing? Not great but worth trying.
Further update on GeneFrames replacements from GraceBio. Recap: their prototypes worked great, and in July they said they were moving to production. I emailed GraceBio beginning of October requesting update about production. Since then I have emailed them 4 times, and have not received any reply. 🔬🦠
November 14, 2025 at 10:39 AM
Further update on GeneFrames replacements from GraceBio. Recap: their prototypes worked great, and in July they said they were moving to production. I emailed GraceBio beginning of October requesting update about production. Since then I have emailed them 4 times, and have not received any reply. 🔬🦠
Thanks for the invite, really looking forward to it!
October 22, 2025 at 8:27 AM
Thanks for the invite, really looking forward to it!