Hala
@scihala.bsky.social
Scientist @ManifoldBio / Multiplex InVivo Biologics / Antibody therapeutics
NeuroPhD from @BrownU / Opsin GPCR signaling / Hypothalamus
NeuroPhD from @BrownU / Opsin GPCR signaling / Hypothalamus
Reposted by Hala
www.fiercebiotech.com/biotech/roch... Shuttles are the future of medicine. Manifold is doing our part 🚀
Roche signs $2B pact to pilot Manifold Bio's shuttles to the brain
Roche may have been exploring ways to shuttle drugs to the brain for well over a decade, but that’s not stopping the pharma from
www.fiercebiotech.com
November 3, 2025 at 2:16 PM
www.fiercebiotech.com/biotech/roch... Shuttles are the future of medicine. Manifold is doing our part 🚀
Very excited to share my PhD work now out @pnas.org! We discovered the cellular mechanism and function of Opsin 3, a light sensing GPCR, in the hypothalamus.
www.pnas.org/doi/10.1073/...
#GPCR #Opsin #MC4R #Kir7.1 #hypothalamus #feeding
www.pnas.org/doi/10.1073/...
#GPCR #Opsin #MC4R #Kir7.1 #hypothalamus #feeding
Hypothalamic opsin 3 suppresses MC4R signaling and potentiates Kir7.1 to promote food consumption | PNAS
Mammalian opsin 3 (OPN3) is a member of the opsin family of G-protein-coupled receptors
with ambiguous light sensitivity. OPN3 was first identified...
www.pnas.org
February 16, 2025 at 4:00 PM
Very excited to share my PhD work now out @pnas.org! We discovered the cellular mechanism and function of Opsin 3, a light sensing GPCR, in the hypothalamus.
www.pnas.org/doi/10.1073/...
#GPCR #Opsin #MC4R #Kir7.1 #hypothalamus #feeding
www.pnas.org/doi/10.1073/...
#GPCR #Opsin #MC4R #Kir7.1 #hypothalamus #feeding