James DiCarlo
scientistjames.bsky.social
James DiCarlo
@scientistjames.bsky.social
I’m a synthetic biologist, clinical pathologist, and drug developer. I also love reef aquariums!
For anyone interested in the esoterica of angelfish taxonomy, I really recommend this article.
December 3, 2024 at 11:54 PM
Reposted by James DiCarlo
Excited to share our latest pre-print, in which we show that greater genetic diversity, rather than sample size alone, improving the accuracy of genetic intolerance metrics

www.biorxiv.org/content/10.1...
Diverse ancestral representation improves genetic intolerance metrics
Rapidly expanding genomic databases have enabled the identification of regions in the human genome intolerant to variation and thus likely relevant to human disease. However, despite their unprecedent...
www.biorxiv.org
November 13, 2024 at 3:17 PM