Elmira
@sciencyelmira.bsky.social
leukemia postdoc in Peggy Goodell’s lab. Houston.
Thank you Josh for all your support, help and encouragement! It is a great pleasure to work with you and your team.
November 5, 2025 at 5:54 PM
Thank you Josh for all your support, help and encouragement! It is a great pleasure to work with you and your team.
We discuss how repurposing of widely used anti-diabetes drugs may offer a strategy for individuals with CH, highlighting precautions like risk-stratification and pointing out future research directions. Open access: rdcu.be/eh0OF
Age-related blood condition counteracted with a common diabetes drug | Nature
Metformin could reduce people’s risk of certain age-associated blood cancers, but more work is needed to identify who is likely to benefit. Metformin could reduce people’s risk of certain age-associated blood cancers, but more work is needed to identify who is likely to benefit.
rdcu.be
April 16, 2025 at 10:19 PM
We discuss how repurposing of widely used anti-diabetes drugs may offer a strategy for individuals with CH, highlighting precautions like risk-stratification and pointing out future research directions. Open access: rdcu.be/eh0OF
DNMT3A mutant cells have reduced methylation at specific loci and a distinct metabolism compared to healthy cells. DNMT3A mutant cells are vulnerable to inhibition of oxidative phosphorylation. Metformin and MitoQ can block CH clone expansion in murine and human models.
April 16, 2025 at 10:19 PM
DNMT3A mutant cells have reduced methylation at specific loci and a distinct metabolism compared to healthy cells. DNMT3A mutant cells are vulnerable to inhibition of oxidative phosphorylation. Metformin and MitoQ can block CH clone expansion in murine and human models.
