MIT scientists have achieved the first-ever lab synthesis of verticillin A, a complex fungal compound discovered in 1970. Its delicate structure stalled chemists for decades, despite differing from related molecules by only two atoms. With the synthesis finally complete, researchers created new variants that showed strong activity against a rare pediatric brain cancer. The breakthrough could unlock an entire class of previously unreachable cancer-fighting molecules.

Some ants thrive by choosing numbers over strength. Instead of heavily protecting each worker, they invest fewer resources in individual armor and produce far more ants. Larger colonies then compensate with collective behaviors like group defense and coordinated foraging. The strategy has been linked to evolutionary success and greater species diversity.

New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early damage in mice and reduces inflammation linked to disease progression. The treatment was given before symptoms appeared, targeting the disease at its earliest stage. Researchers say this approach could reshape how Alzheimer’s is prevented and treated.

How you walk may matter just as much as how much you walk. A large UK study tracking more than 33,000 low-activity adults found that people who grouped their daily steps into longer, uninterrupted walks had dramatically lower risks of early death and heart disease than those who moved in short, scattered bursts.

Black holes are among the most extreme objects in the universe, and now scientists can model them more accurately than ever before. By combining Einstein’s gravity with realistic behavior of light and matter, researchers have built simulations that closely match real astronomical observations. These models reveal how matter forms chaotic, glowing disks and launches powerful outflows as it falls into black holes. It’s a major step toward decoding how these cosmic engines actually work.

A new AI developed at Duke University can uncover simple, readable rules behind extremely complex systems. It studies how systems evolve over time and reduces thousands of variables into compact equations that still capture real behavior. The method works across physics, engineering, climate science, and biology. Researchers say it could help scientists understand systems where traditional equations are missing or too complicated to write down.

A Brazilian study has confirmed that Joseph’s Coat, a plant used for generations in folk medicine, can significantly reduce inflammation and arthritis symptoms in lab tests. Researchers observed less swelling, healthier joints, and signs of tissue protection. Just as important, the extract showed a promising safety profile at tested doses. The discovery could pave the way for new plant-based anti-inflammatory treatments.

Eating full-fat cheese and cream may be associated with a lower risk of dementia, according to a large study that tracked people for more than 25 years. Those who consumed higher amounts of these foods developed dementia less often than those who ate little or none. Interestingly, low-fat dairy products did not show the same pattern. Researchers caution that the findings show an association, not cause and effect.

Scientists have uncovered a missing feedback in Earth’s carbon cycle that could cause global warming to overshoot into an ice age. As the planet warms, nutrient-rich runoff fuels plankton blooms that bury huge amounts of carbon in the ocean. In low-oxygen conditions, this process can spiral out of control, cooling Earth far beyond its original state. While this won’t save us from modern climate change, it may explain Earth’s most extreme ancient ice ages.

Researchers studying a massive landslide in Alaska have detected strange seasonal seismic pulses caused by water freezing and thawing in rock cracks. These faint signals could become an important early clue to changes that might someday trigger a dangerous landslide-driven tsunami.

A major international review has upended long-held ideas about how top performers are made. By analyzing nearly 35,000 elite achievers across science, music, chess, and sports, researchers found that early stars rarely become adult superstars. Most world-class performers developed slowly and explored multiple fields before specializing. The message is clear: talent grows through variety, not narrow focus.

Sediments from a Roman latrine at Vindolanda show soldiers were infected with multiple intestinal parasites, including roundworm, whipworm, and Giardia — the first time Giardia has been identified in Roman Britain. These parasites spread through contaminated food and water, causing diarrhea, weakness, and long-term illness. Even with sewers and communal toilets, infections passed easily between soldiers. The discovery highlights how harsh and unhealthy life could be on Rome’s northern frontier.

Spanish researchers have created a powerful new open-source tool that helps uncover the hidden genetic networks driving cancer. Called RNACOREX, the software can analyze thousands of molecular interactions at once, revealing how genes communicate inside tumors and how those signals relate to patient survival. Tested across 13 different cancer types using international data, the tool matches the predictive power of advanced AI systems—while offering something rare in modern analytics: clear, interpretable explanations that help scientists understand why tumors behave the way they do.

Superconductors promise loss-free electricity, but most only work at extreme cold. Hydrogen-rich materials changed that—yet their inner workings remained hidden because they only exist under enormous pressure. Now, researchers have directly measured the superconducting state of hydrogen sulfide using a novel tunneling method, confirming how its electrons pair so efficiently. The discovery brings room-temperature superconductors a step closer to reality.

By studying tiny distortions in the shapes of distant galaxies, scientists mapped dark matter and dark energy across one of the largest sky surveys ever assembled. Their results back the standard picture of the universe and show that even archival telescope images can unlock cosmic mysteries.

Old military air samples turned out to be a treasure trove of biological DNA, allowing scientists to track moss spores over 35 years. The results show mosses now release spores up to a month earlier than in the 1990s. Even more surprising, the timing depends more on last year’s climate than current spring conditions. It’s a striking example of how fast ecosystems are adjusting to a warming world.

A major new meta-analysis finds that vegetarian and vegan diets can support healthy growth in children when properly planned. Kids on plant-based diets often had better heart health markers, including lower “bad” cholesterol, and consumed more fiber and vitamins. But the study also flagged common nutrient gaps—especially vitamin B12 and calcium—without supplementation. Experts say plant-based eating is achievable for kids, but only with careful planning.

Balanophora is a plant that abandoned photosynthesis long ago and now lives entirely as a parasite on tree roots, hidden in dark forest undergrowth. Scientists surveying rare populations across East Asian islands uncovered how its cellular machinery shrank but didn’t disappear, revealing unexpected similarities to parasites like malaria. Some island species even reproduce without sex, cloning themselves to colonize new habitats. This strange survival strategy comes with risks, leaving the plant highly vulnerable to habitat loss.

An instrument aboard NASA’s Europa Clipper spacecraft captured rare ultraviolet observations of an interstellar comet while Earth-based telescopes were blinded by the Sun. The spacecraft’s unique position provided an unprecedented look at the comet’s dust and plasma tails from an unusual angle. Scientists detected hydrogen, oxygen, and signs of intense gas release, hinting at powerful activity after the comet’s closest approach to the Sun. The findings may reveal clues about how comets form around other stars.

For years, scientists thought Saturn’s moon Titan hid a global ocean beneath its frozen surface. A new look at Cassini data now suggests something very different: a thick, slushy interior with pockets of liquid water rather than an open sea. A subtle delay in how Titan deforms under Saturn’s gravity revealed this stickier structure. These slushy environments could still be promising places to search for life.

Long before opioids flooded communities, something else was quietly changing—and it may have helped set the stage for today’s crisis. A new study finds that as church attendance dropped among middle-aged, less educated white Americans, deaths from overdoses, suicide, and alcohol-related disease began to rise. The trend started years before OxyContin appeared, suggesting the opioid epidemic intensified a problem already underway.

Getting ahead financially is mainly about what you earn at work, not what you make from investments. Researchers found that promotions, skills, and better jobs drive most upward income movement. But when people slip backward, falling investment income is usually the main reason. Labor builds income steadily; capital is riskier and more unpredictable.

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human astrocytes, scientists identified around 150 that truly influence gene activity—many tied to known Alzheimer’s risk genes. The findings help explain why many disease-linked genetic changes sit outside genes themselves. The resulting dataset is now being used to train AI systems to predict gene control more accurately.

In a rare and historic achievement, Children’s Hospital Colorado successfully completed its first dual heart and liver transplant in a pediatric patient. The life-saving surgery was performed on 11-year-old Gracie Greenlaw, whose congenital heart condition eventually led to liver failure. Dozens of specialists worked together for years to prepare for a moment like this, executing a complex, 16-hour operation. Now months later, Gracie is home, in school, and thriving.

Spending a few hours a week helping others may slow the aging of the brain. Researchers found that both formal volunteering and informal acts, like helping neighbors or relatives, were linked to noticeably slower cognitive decline over time. The benefits added up year after year and didn’t require a huge time commitment. Even modest, everyday helping packed a powerful mental payoff.