This account is run by the members of the Schwalbe lab.
https://schwalbe-lab.de/
#nmr #biomolecules #rna #proteins #dna #drugtargeting #interactions
Lucia covers the technological developments in drug screening by in-cell NMR, supported by Fragment-Screen
fragmentscreen.org @schwalbe-lab.bsky.social @cerm-cirmmp.bsky.social @tumunich.bsky.social
Lucia covers the technological developments in drug screening by in-cell NMR, supported by Fragment-Screen
fragmentscreen.org @schwalbe-lab.bsky.social @cerm-cirmmp.bsky.social @tumunich.bsky.social
Full text: academic.oup.com/nar/article/...
#G4 #G-Quadruplex #NMR #smFRET #ChIP-qPCR
Full text: academic.oup.com/nar/article/...
#G4 #G-Quadruplex #NMR #smFRET #ChIP-qPCR
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#SARSCoV2 #NMR #drugtargeting #synthesis
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#SARSCoV2 #NMR #drugtargeting #synthesis
Prof. Schwalbe is coordinator of the Fragment-Screen project, developing new tools for fragment-based drug discovery
Find out more here - fragmentscreen.org/home @schwalbe-lab.bsky.social
Prof. Schwalbe is coordinator of the Fragment-Screen project, developing new tools for fragment-based drug discovery
Find out more here - fragmentscreen.org/home @schwalbe-lab.bsky.social
instruct-eric.org/news/profess...
instruct-eric.org/news/profess...
Full text: www.sciencedirect.com/science/arti...
#NMR #Ephrin #Cancer #receptor
Full text: www.sciencedirect.com/science/arti...
#NMR #Ephrin #Cancer #receptor
"Noncanonical RNA binding of human La-related protein 6"
Full text: academic.oup.com/nar/article/...
#LARP #NMR #RNA #structure
"Noncanonical RNA binding of human La-related protein 6"
Full text: academic.oup.com/nar/article/...
#LARP #NMR #RNA #structure
"Dimerization propensity of the β1-adrenergic receptor in lipid nanodiscs probed by DEER and single-molecule spectroscopies"
Full text: www.pnas.org/doi/10.1073/...
#DEER #protein #SingleMolecule #GPCR
"Dimerization propensity of the β1-adrenergic receptor in lipid nanodiscs probed by DEER and single-molecule spectroscopies"
Full text: www.pnas.org/doi/10.1073/...
#DEER #protein #SingleMolecule #GPCR
Full text: m.rnajournal.cshlp.org/content/earl...
#NMR #MD #RNA #SARSCoV2 #structure #dynamics
Full text: m.rnajournal.cshlp.org/content/earl...
#NMR #MD #RNA #SARSCoV2 #structure #dynamics
@instruct-eric.bsky.social @gdch.de
#NMR #EPR #FGMR #GDCh #InstructERIC
@instruct-eric.bsky.social @gdch.de
#NMR #EPR #FGMR #GDCh #InstructERIC
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
www1.bio.ku.dk/english/rese... @schwalbe-lab.bsky.social
Researchers in Denmark can receive access to Instruct technologies and instrumentation here - instruct-eric.org/submit-propo...
www1.bio.ku.dk/english/rese... @schwalbe-lab.bsky.social
Researchers in Denmark can receive access to Instruct technologies and instrumentation here - instruct-eric.org/submit-propo...
Using fragment-growth guided by NMR spectroscopy, we optimized small molecules targeting SCoV-2 SL1 RNA, integrating solubility, affinity, and specificity to identify translation inhibitors.
Full text: pubs.acs.org/doi/10.1021/...
#NMR #drugdesign #RNA #SARSCoV2
Using fragment-growth guided by NMR spectroscopy, we optimized small molecules targeting SCoV-2 SL1 RNA, integrating solubility, affinity, and specificity to identify translation inhibitors.
Full text: pubs.acs.org/doi/10.1021/...
#NMR #drugdesign #RNA #SARSCoV2
We used NMR to characterize the SL5a stem-loop from HCoV-229E, a conserved RNA element key to coronavirus RNA translation and replication.
doi.org/10.1007/s121...
#RNA #NMR #Virology #StructuralBiology #Assignment #Coronavirus
We used NMR to characterize the SL5a stem-loop from HCoV-229E, a conserved RNA element key to coronavirus RNA translation and replication.
doi.org/10.1007/s121...
#RNA #NMR #Virology #StructuralBiology #Assignment #Coronavirus
A fantastic lineup of prize winners:
🏆 Prof. Thomas Prisner – Richard R. Ernst Prize
🏆 Dr. Nergiz Sahin Solmaz – Raymond Andrew Prize
🏆 Prof. Tuo Wang – Ampere Prize for Young Investigators
Congratulations to all!
#EUROMAR2025 #NMR #EPR #MRI #ESR #NMRchat
"NMR screening of low molecular weight inhibitors targeting the papain-like protease (PLPro) of SARS-CoV-2"
Full text: febs.onlinelibrary.wiley.com/doi/10.1002/...
#screening #NMR #SARS-CoV2 #targeting
"NMR screening of low molecular weight inhibitors targeting the papain-like protease (PLPro) of SARS-CoV-2"
Full text: febs.onlinelibrary.wiley.com/doi/10.1002/...
#screening #NMR #SARS-CoV2 #targeting
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
actionnetwork.org/petitions/op...
actionnetwork.org/petitions/op...
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
@instruct-eric.bsky.social
instruct-eric.org/news/instruc...
@instruct-eric.bsky.social
instruct-eric.org/news/instruc...
"Structural Insights into Spare-Tire DNA G-Quadruplex from the Human VEGF Promoter"
Full text: pubs.acs.org/doi/10.1021/...
#G4 #quadruplex #photocages #NMR #VEGF #structure
"Structural Insights into Spare-Tire DNA G-Quadruplex from the Human VEGF Promoter"
Full text: pubs.acs.org/doi/10.1021/...
#G4 #quadruplex #photocages #NMR #VEGF #structure
Full text:
link.springer.com/article/10.1...
Full text:
link.springer.com/article/10.1...