Schumacher Lab
@schumacher-lab.bsky.social
We use a technology-based approach to understand how our T cells recognize cancer. @nkinl.bsky.social | Tweets from lab members
It's not the models, it's the data!
We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models.
www.biorxiv.org/content/10.1...
We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models.
www.biorxiv.org/content/10.1...
A functionally validated TCR-pMHC database for TCR specificity model development
Accurate prediction of TCR specificity forms a holy grail in immunology and large language models and computational structure predictions provide a path to achieve this. Importantly, current TCR-pMHC ...
www.biorxiv.org
May 2, 2025 at 3:57 PM
It's not the models, it's the data!
We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models.
www.biorxiv.org/content/10.1...
We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models.
www.biorxiv.org/content/10.1...
Reposted by Schumacher Lab
🌟Keystone Cancer Immunotherapy conference 2025 🌟 Speaker Highlight #2 at #KSCancerImmune25: Dr. Ton N. Schumacher @nkinl.bsky.social will discuss how T cells detect tumors in “Dissecting T Cell Recognition of Cancer.” Don’t miss his cutting-edge immunology insights!
January 6, 2025 at 11:07 PM
🌟Keystone Cancer Immunotherapy conference 2025 🌟 Speaker Highlight #2 at #KSCancerImmune25: Dr. Ton N. Schumacher @nkinl.bsky.social will discuss how T cells detect tumors in “Dissecting T Cell Recognition of Cancer.” Don’t miss his cutting-edge immunology insights!
Reposted by Schumacher Lab
🏆 Congrats to Ton Schumacher of the NKI and Oncode Institute for receiving the ESMO Award for Immuno-Oncology 2024! His work on T-cells and immunotherapy is revolutionizing cancer treatment ➡️ t.co/WHlqDB7fjF
December 13, 2024 at 8:49 AM
🏆 Congrats to Ton Schumacher of the NKI and Oncode Institute for receiving the ESMO Award for Immuno-Oncology 2024! His work on T-cells and immunotherapy is revolutionizing cancer treatment ➡️ t.co/WHlqDB7fjF