Michael
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schlierflab.bsky.social
Michael
@schlierflab.bsky.social
single-molecule aficionado, antibiotic resistances
Prof at TUD
@tudresden.bsky.social Alum: UIUC, TUM
@tum.de, LMU @lmumuenchen.bsky.social, U Paris XI
Au revoir #mifobio2025. It was a fantastique, inspiring meeting- merci beaucoup for the invite and the great organization and all the workshops from homebuilt microscopes to the newest company developments. 🤩
October 17, 2025 at 9:00 AM
Merci @amazeld.bsky.social et Kévin for the great discussions and time during my short visit @institutpasteur.bsky.social. Always enjoyable to be in Paris.
July 7, 2025 at 1:04 PM
JOB OPENING for biochemist/-physicst 🧑‍🔬: This isn't an official job ad yet. We are looking for a postdoc working on large to high throughout single-molecule FRET on protein structures and dynamics. The project will be run in our lab and co-directed jointly with a team from big pharma/biotech. 1/2
June 17, 2025 at 3:05 PM
Day 3 of #BPS2025 and presentation 3 of Schlierf lab. Join César’s double feature with a talk at 12.35pm in room 501ABC and then a poster B561 starting at 1.45pm. He talks about magnetic tweezers so join and the force may be with you. 💪🔬
February 18, 2025 at 2:52 PM
Ready for Schlierf lab presentation #2 at #BPS2025 ? Tomorrow morning (yes, you will have to get up early) - Pilar will present her studies on LexA and the chromosome and … with beautiful 🤩 multicolor superres Room 515B at 8.45. Be there or be ◼️.
February 17, 2025 at 3:04 AM
Ready to welcome you today in the afternoon ~ 2 pm 🧬🔥🧫 - poster B202
February 16, 2025 at 4:36 PM
BCUBE reps on the way to LA. Looking forward to an exciting BPS meeting with lots of science and seeing/making friends @jamessaenz.bsky.social @anh-nhn.bsky.social @cmcb-tud.bsky.social
February 14, 2025 at 11:01 AM
Great to have @joshmoore.bsky.social here @cmcb-tud.bsky.social sharing his vision on scalable strategies for FAIR image management.
January 16, 2025 at 12:08 PM
..while our collaborators determined recombination efficiencies in vivo showing a strong correlation between mechanical stability and recombination efficiency. Why is force a determinant? Take a look at our paper and find out even more - Can we use this to reduce bacterial adaptation? 4/4.
December 13, 2024 at 7:38 PM
Using force spectroscopy data, we quantified mechanical stability of the synaptic complex formed by two recombination sites and four recombinases and disintegration pathways - and additionally introduced protein mutations to dissect the molecular contributors to stability... 3/4
December 13, 2024 at 7:38 PM
We wondered whether the recombination efficiency correlates with the synaptic complex stability and developed a single-molecule optical tweezers @lumicks.bsky.social assay. We probed the stability of hundreds of synaptic complexes with many different recombination sites... 2/4
December 13, 2024 at 7:38 PM
Very happy to see our study "printed" www.science.org/doi/10.1126/.... We report how mechanics are related with DNA recombination efficiency. Great work by Kate @cmcb-tud.bsky.social @tudresden.bsky.social in collab with @celineloot.bsky.social and @amazeld.bsky.social @pasteur.fr . Synopsis 👇1/4
December 13, 2024 at 7:38 PM
Very happy to graduate the first generation of Master of Science Physics of Life students. Congrats to all of you 🎉🍾. It was a pleasure to guide you as a dean of studies!
@tudresden.bsky.social @poldresden.bsky.social

(photo credit: Magda Gonciarz)
November 25, 2024 at 8:55 AM