Jacob Schimelman, PhD
@schimelman.bsky.social
Neuroregeneration, Polymeric Biomaterials, Tissue Engineering, Bioprinting with Light • Pessoptimist for reforming academia • UG @CWRUMacro • CT, NC Raised
https://scholar.google.com/citations?user=Fg0US2sAAAAJ&hl=en
https://scholar.google.com/citations?user=Fg0US2sAAAAJ&hl=en
what in the dystopian hell is this
November 14, 2025 at 3:34 AM
what in the dystopian hell is this
This is insanely evil.
The GOP uses ignorance as a shield to enact their unpopular policy agendas of the 1%
The GOP uses ignorance as a shield to enact their unpopular policy agendas of the 1%
September 20, 2025 at 9:04 PM
This is insanely evil.
The GOP uses ignorance as a shield to enact their unpopular policy agendas of the 1%
The GOP uses ignorance as a shield to enact their unpopular policy agendas of the 1%
The thought was triggered by this figure in the publication.
September 19, 2025 at 8:21 PM
The thought was triggered by this figure in the publication.
UCSD is the only UC campus to restock on military-grade lethal ammunition for *campus* police.
This is highly concerning.
This is highly concerning.
September 18, 2025 at 2:42 AM
UCSD is the only UC campus to restock on military-grade lethal ammunition for *campus* police.
This is highly concerning.
This is highly concerning.
It was the Juke and was before its time.
September 9, 2025 at 7:42 PM
It was the Juke and was before its time.
at least ChatGPT knows sama's a liar lol
August 7, 2025 at 8:21 PM
at least ChatGPT knows sama's a liar lol
August 6, 2025 at 12:34 AM
truly tragic how much toxic individualism runs Texas..
July 7, 2025 at 6:54 PM
truly tragic how much toxic individualism runs Texas..
The similarities are striking. The difference is is that our voters and politicians have no excuse of not have a historical frame of reference.
Hitler's version of the Nazi party won out by persuading the Catholic wing of being granted protection and their desires.
Hitler's version of the Nazi party won out by persuading the Catholic wing of being granted protection and their desires.
July 1, 2025 at 6:14 PM
The similarities are striking. The difference is is that our voters and politicians have no excuse of not have a historical frame of reference.
Hitler's version of the Nazi party won out by persuading the Catholic wing of being granted protection and their desires.
Hitler's version of the Nazi party won out by persuading the Catholic wing of being granted protection and their desires.
provides her direct analysis of the literature and misstates conclusions of peer-reviewed work. This example is damning. She claims that this *one* non-comprehensive meta-analysis states that it's debatable if hormone therapy directly improves mental health conditions, but it doesn't 2/n
June 30, 2025 at 2:22 AM
provides her direct analysis of the literature and misstates conclusions of peer-reviewed work. This example is damning. She claims that this *one* non-comprehensive meta-analysis states that it's debatable if hormone therapy directly improves mental health conditions, but it doesn't 2/n
Senator Bernie Sanders (D-VT) agrees.
June 22, 2025 at 1:20 AM
Senator Bernie Sanders (D-VT) agrees.
It's past time to impeach the President due to his complete disregard of our Constitutional democracy and the welfare of our nation.
Rep. Massie seems to agree (R-KY)
Rep. Massie seems to agree (R-KY)
June 22, 2025 at 1:06 AM
It's past time to impeach the President due to his complete disregard of our Constitutional democracy and the welfare of our nation.
Rep. Massie seems to agree (R-KY)
Rep. Massie seems to agree (R-KY)
We need to be vocal to stand up for our colleagues and students who are Chinese nationals.
The analogue NIH & FBI China Initiatives have led to numerous false accusations of US profs with familial ties to China, which resulted in ruined careers and, in at least one case, suicide.
The analogue NIH & FBI China Initiatives have led to numerous false accusations of US profs with familial ties to China, which resulted in ruined careers and, in at least one case, suicide.
May 29, 2025 at 6:04 AM
We need to be vocal to stand up for our colleagues and students who are Chinese nationals.
The analogue NIH & FBI China Initiatives have led to numerous false accusations of US profs with familial ties to China, which resulted in ruined careers and, in at least one case, suicide.
The analogue NIH & FBI China Initiatives have led to numerous false accusations of US profs with familial ties to China, which resulted in ruined careers and, in at least one case, suicide.
All NIH training grants appear to have been eliminated.
May 11, 2025 at 7:08 AM
All NIH training grants appear to have been eliminated.
Glad to see it happening!! Meanwhile my rep is putting his efforts into bipartisan grandstanding..
May 10, 2025 at 1:43 AM
Glad to see it happening!! Meanwhile my rep is putting his efforts into bipartisan grandstanding..
(via dynamic gait analysis).
Further studies are needed to assess the performance of this conduit design for wider defect sites in larger animal models. We hypothesize that the effect of the enhanced vascularization found in the micro-porous conduits will be more pronounced. 5/n
Further studies are needed to assess the performance of this conduit design for wider defect sites in larger animal models. We hypothesize that the effect of the enhanced vascularization found in the micro-porous conduits will be more pronounced. 5/n
May 7, 2025 at 7:52 PM
(via dynamic gait analysis).
Further studies are needed to assess the performance of this conduit design for wider defect sites in larger animal models. We hypothesize that the effect of the enhanced vascularization found in the micro-porous conduits will be more pronounced. 5/n
Further studies are needed to assess the performance of this conduit design for wider defect sites in larger animal models. We hypothesize that the effect of the enhanced vascularization found in the micro-porous conduits will be more pronounced. 5/n
Both conduit design variants (w/ & w/o micropores) resulted in functional nerve regeneration in a mouse sciatic nerve model (via CMAP electrophys) on par with the clinical standard surgical intervention, a reverse polarity autograft. Further, both conduits led to recovery of bulk motor function. 4/n
May 7, 2025 at 7:52 PM
Both conduit design variants (w/ & w/o micropores) resulted in functional nerve regeneration in a mouse sciatic nerve model (via CMAP electrophys) on par with the clinical standard surgical intervention, a reverse polarity autograft. Further, both conduits led to recovery of bulk motor function. 4/n
recently been commercialized as the Cellink Bionova X). This DMD-based system is able to achieve up to 1um xy resolution.
We designed a conduit with dense hexagonal microchannels for axon guidance and explored including orthogonal, patterned micropores to enhance extraneural vascularization. 3/n
We designed a conduit with dense hexagonal microchannels for axon guidance and explored including orthogonal, patterned micropores to enhance extraneural vascularization. 3/n
May 7, 2025 at 7:52 PM
recently been commercialized as the Cellink Bionova X). This DMD-based system is able to achieve up to 1um xy resolution.
We designed a conduit with dense hexagonal microchannels for axon guidance and explored including orthogonal, patterned micropores to enhance extraneural vascularization. 3/n
We designed a conduit with dense hexagonal microchannels for axon guidance and explored including orthogonal, patterned micropores to enhance extraneural vascularization. 3/n
We set out to develop a synthetic nerve guidance conduit that can effectively result in functional motor nerve regeneration by material properties alone, namely microtopology and stiffness.
We were able to achieve this using the Chen lab's custom-designed RaPID bioprinting system (which has
2/n
We were able to achieve this using the Chen lab's custom-designed RaPID bioprinting system (which has
2/n
May 7, 2025 at 7:52 PM
We set out to develop a synthetic nerve guidance conduit that can effectively result in functional motor nerve regeneration by material properties alone, namely microtopology and stiffness.
We were able to achieve this using the Chen lab's custom-designed RaPID bioprinting system (which has
2/n
We were able to achieve this using the Chen lab's custom-designed RaPID bioprinting system (which has
2/n
I'm happy to share the first pre-print from the Shaochen Chen lab!
A major obstacle in translating engineered nerve guidance conduits from the lab to the clinic is the inclusion of biologics such as bioactive molecules and cells, which results in a device with the highest FDA regulatory burden. 1/n
A major obstacle in translating engineered nerve guidance conduits from the lab to the clinic is the inclusion of biologics such as bioactive molecules and cells, which results in a device with the highest FDA regulatory burden. 1/n
May 7, 2025 at 7:52 PM
I'm happy to share the first pre-print from the Shaochen Chen lab!
A major obstacle in translating engineered nerve guidance conduits from the lab to the clinic is the inclusion of biologics such as bioactive molecules and cells, which results in a device with the highest FDA regulatory burden. 1/n
A major obstacle in translating engineered nerve guidance conduits from the lab to the clinic is the inclusion of biologics such as bioactive molecules and cells, which results in a device with the highest FDA regulatory burden. 1/n
April 12, 2025 at 8:50 PM
Americans dared to have a government and society that strove to work for everyone.
These people spit on the ideals of the Declaration of Independence and the modern Constitution.
Science is only as good as the people undertaking it.
These people spit on the ideals of the Declaration of Independence and the modern Constitution.
Science is only as good as the people undertaking it.
March 29, 2025 at 9:09 PM
Americans dared to have a government and society that strove to work for everyone.
These people spit on the ideals of the Declaration of Independence and the modern Constitution.
Science is only as good as the people undertaking it.
These people spit on the ideals of the Declaration of Independence and the modern Constitution.
Science is only as good as the people undertaking it.