Sarina Ravens
sarinaravens.bsky.social
Sarina Ravens
@sarinaravens.bsky.social
Immunologist, Associate professor for Human Systems Immunology at Hannover Medical School, Enthusiast for gamma/delta T cells
Reposted by Sarina Ravens
📣 New preprint drop! In #ScienceImmunology, we found that regulatory #CD39 γδ IELs are reduced in #IBD, now @saraalonsomera.bsky.social shows that gut #microbiota promote enhanced CD39 expression in γδ IELs through #TCR and IL-15 activation. #gdTcells #GIresearch #Gastrosky @sinaiimmuno.bsky.social
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling https://www.biorxiv.org/content/10.1101/2025.03.22.644616v1
March 26, 2025 at 2:26 PM
Reposted by Sarina Ravens
As expected, #gd2025 is as delightful as ever! Glad I could bring Irving & @saraalonsomera.bsky.social to hang out with our #gdTcell crew including @sarinaravens.bsky.social, @coffeltlab.bsky.social, @immunowolf.bsky.social, and Julie Jameson 🤩 Miss you @lydialynch.bsky.social!
May 23, 2025 at 4:24 AM
Reposted by Sarina Ravens
The perfect end to a great #gammadeltatoronto conference: our latest review has just been published in Advances in Immunology!

"Modulation of humoral immunity by γδ T cells: A potential adjuvant strategy for vaccination"

👉🏼 authors.elsevier.com/a/1l8ltErwXf...

#gdTcells @forum-gd.bsky.social
May 23, 2025 at 8:37 PM
Reposted by Sarina Ravens
Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer.

#gdTcells
Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer - Nature Cancer
Silva-Santos and colleagues provide in vivo preclinical evidence supporting a therapeutic use of Delta One T cells to tackle colorectal cancer and propose activating natural killer cell receptor NKG2D...
www.nature.com
April 17, 2025 at 10:22 AM
Reposted by Sarina Ravens
Woohoo! We’re sooo glad we had an excuse to bring @joanabmartins.bsky.social back to the magical land of #gdTcells! #GIresearch @sinaiimmuno.bsky.social
I’m happy to share that I’m starting a new position as Postdoctoral Researcher at @edelblumlab.bsky.social at Icahn School of Medicine at Mount Sinai!

After years away from γδ T cell research, I am finally back!! 🥳🥳🥳

#gdTcells #gutimmunology
March 11, 2025 at 6:35 PM
Reposted by Sarina Ravens
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.
www.science.org
March 21, 2025 at 6:14 PM
Reposted by Sarina Ravens
📰✨ Wir sind sehr happy darüber, dass wir Infect-Net in der aktuellen Ausgabe des #BioSpektrums vorstellen durften! 🚀
Schaut mal rein:
👀👉 rdcu.be/efwbV

@gbmev.bsky.social @vaam-microbes.bsky.social @vbio.bsky.social @gabrielepradel.bsky.social @kkubatzky.bsky.social
Netzwerk für Infektionsforscherinnen
rdcu.be
March 28, 2025 at 3:27 PM
Thanks for the excellent organisation and inspiring discussions and presentations at the Network-Meeting!
#infectnetIV Recap: Unser 4. Netzwerktreffen am 21. und 22. November 2024 wurde gemeinsam mit dem Centrum für #Infektionsmedizin (CIM) der @uniklinikkoeln.bsky.social organisiert. Vielen Dank für die gemeinsame Aktion und die tolle Zusammenarbeit. Wir freuen auf viele weitere CIM-Forscherinnen! 🤝💜
November 25, 2024 at 12:22 PM
Reposted by Sarina Ravens
#infectnetIV Recap: #Pädiatrie der nächsten Generation präsentierte Dorothee Viemann vom Uniklinikum Würzburg. Die #Infektiologin zeigte ihre neueste Ergebnisse zum Einfluß des Pandemie-Lockdowns auf die Entwicklung des Immunsystems von Neugeborenen! #UKWürzburg #neonataleimmunität 👶💜
November 24, 2024 at 11:13 AM
Reposted by Sarina Ravens
#infectnetIV Recap: Infektiologin Dr. Annika Claßen ist Expertin für #Bakteriophagen am #CIM der @uniklinikkoeln.bsky.social und hat uns über den Entwicklungsstand einer Leitlinie für die individualisierte #Phagentherapie und deren regulatorische Herausforderungen informiert. 🦠🚫💜 #Phagen #AMR
November 24, 2024 at 12:05 PM
Reposted by Sarina Ravens
#infectnetIV Recap: Are we lost in translation? Marylyn Addo vom Universitätsklinikum Hamburg-Eppendorf präsentiere einen Überblick über die Translationsprojekte des #DZIF: #Translation ist teuer, langwierig und erfordert effiziente interdisziplinäre #Teamarbeit! #Infektionsforschung #womeninSTEM 💜
November 24, 2024 at 10:35 AM
What a nice opportunity for the first post here @bsky.app
We studied gd T cells in children with congenital heart disease @forum-gd.bsky.social .
Congratulations to the entire team and happy to see it out @naturecomms.bsky.social .

www.nature.com/articles/s41...
Early-life thymectomy leads to an increase of granzyme-producing γδ T cells in children with congenital heart disease - Nature Communications
Congenital heart disease (CHD) is often treated with cardiac surgery in infancy, which involves the removal of the thymus, due to its position in the chest. Here authors show that the γδ T cell compar...
www.nature.com
November 25, 2024 at 12:16 PM