Indeed, they have a fantastic Instagram and design! ❤️

💡 Orthogroup fixation frequency = proportion of species where the orthogroup is part of the species-level core genome relative to the number of species where the orthogroup is part of the species-level pangenome  --> new concept thanks to tool

Stijn Wittouck applied the core, sample and pan modules to infer a representative pangenome for over 31,000 (!) genomes of the order #Lactobacillales – without use of super computer!

Applicable for all taxa, but of course we used it for our favorite bacteria #lactobacilli: when ran on a dataset of 720 genomes of the genus #Lactiplantibacillus, this resulted in the identification of 2,093 core genes in 11 (!) minutes

🏆 When benchmarked against existing tools, the SCARAP pan module proved up to an order of magnitude faster with comparable accuracy

SCARAP contains three modules for #comparative #genomics analyses of bacteria 🧬
(1)     a fast and scalable pangenome inference module
(2)     a direct core genome inference module 
(3)     a module for subsampling representative genomes in linear time