Sanketh Vedula
@sankethvedula.bsky.social
PhD student @ Technion, Israel.
Reposted by Sanketh Vedula
📢 New preprint, lead by Alex Bronstein, @sankethvedula.bsky.social and colleagues:
Guiding AlphaFold with experimental data.
This approach generates conformational ensembles guided by NMR, X-ray (or whatever) data. I am thrilled to tackle lots of exciting problems with it!
arxiv.org/abs/2502.09372
Guiding AlphaFold with experimental data.
This approach generates conformational ensembles guided by NMR, X-ray (or whatever) data. I am thrilled to tackle lots of exciting problems with it!
arxiv.org/abs/2502.09372
Inverse problems with experiment-guided AlphaFold
Proteins exist as a dynamic ensemble of multiple conformations, and these motions are often crucial for their functions. However, current structure prediction methods predominantly yield a single conf...
arxiv.org
February 17, 2025 at 4:35 PM
📢 New preprint, lead by Alex Bronstein, @sankethvedula.bsky.social and colleagues:
Guiding AlphaFold with experimental data.
This approach generates conformational ensembles guided by NMR, X-ray (or whatever) data. I am thrilled to tackle lots of exciting problems with it!
arxiv.org/abs/2502.09372
Guiding AlphaFold with experimental data.
This approach generates conformational ensembles guided by NMR, X-ray (or whatever) data. I am thrilled to tackle lots of exciting problems with it!
arxiv.org/abs/2502.09372
Our recent work presented as a talk at the MLSB workshop in NeurIPS.
Next up - Contributed Talk!
Generative modeling of protein ensembles guided by crystallographic electron densities
Sai Advaith Maddipatla · Nadav Sellam · @sankethvedula.bsky.social · Ailie Marx · Alex Bronstein
Generative modeling of protein ensembles guided by crystallographic electron densities
Sai Advaith Maddipatla · Nadav Sellam · @sankethvedula.bsky.social · Ailie Marx · Alex Bronstein
December 15, 2024 at 10:05 PM
Our recent work presented as a talk at the MLSB workshop in NeurIPS.