Sanjat Kanjilal
@sanjatkanjilal.bsky.social
Group leader | Dept of Medical Microbiology | Amsterdam University Medical Center @amsterdamumc.bsky.social | research machine learning for dx/tx/prevention of infectious diseases
It is hard to know what durations of treatment best prevent the selection of resistance at the population level; this is partly on the basis of data that suggests most people develop resistance post treatment through exogenous colonization of a damaged microbiome, rather than endogenous evolution.
November 24, 2025 at 10:37 AM
It is hard to know what durations of treatment best prevent the selection of resistance at the population level; this is partly on the basis of data that suggests most people develop resistance post treatment through exogenous colonization of a damaged microbiome, rather than endogenous evolution.
Sorry for the delayed reply; been a while since I thought of this but yes my recollection is that since BAL samples are ~50mls, we centrifuge prior to Gram staining and aliquot 0.01ml for quantitative culture. Happy to inquire with folks on the bench if that would be of help!
November 7, 2025 at 7:54 AM
Sorry for the delayed reply; been a while since I thought of this but yes my recollection is that since BAL samples are ~50mls, we centrifuge prior to Gram staining and aliquot 0.01ml for quantitative culture. Happy to inquire with folks on the bench if that would be of help!