Our #Paramecium artwork is featured on the cover of #NAR! doi.org/10.1093/nar/...

The 2nd edition of the Paris-Munich Epigenetics meeting will be held April 9-11, 2025 in Paris. Attendance is free of charge.

Please visit the website
www.sfb1064.med.uni-muenchen.de/paris_munich...
to find out more about the program and to register. #epigenetics

Here, we discover that the selective degradation of scnRNAs corresponding to non-TE sequences requires the Paramecium nuclear protein Gtsf1, which we show interacts with the scnRNA binding protein Ptiwi09. (5/8)

produces scnRNAs from both TE and non-TE sequences. Then, the subset of scnRNAs that correspond to TEs is selected and triggers the physical removal of TEs from the genome, a definitive form of TE silencing. (4/8)