Dr Samantha Nixon
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samnscience.bsky.social
Dr Samantha Nixon
@samnscience.bsky.social
Venoms and toxin researcher studying molecular basis of toxin resistance. Former arachnophobe turned spider advocate. Current postdoc at UCSF. PhD at UQ. 🇦🇺 in 🇺🇸
Excited to share our latest paper! We show that frog proteins bind and functionally neurotoxins involved in paralytic shellfish poisoning, with exciting potential applications in diagnostics and therapies!

www.nature.com/articles/s41...
Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins - Nature Communications
Dinoflagellates and cyanobacteria produce saxitoxin (STX) congeners that block voltage-gated sodium channels. Here authors show how amphibians may sequester STX congeners using a ‘lock and key’ mode, ...
www.nature.com
May 1, 2025 at 8:09 PM
Reposted by Dr Samantha Nixon
New insights from our group into how frogs resist toxic environments published today! 🎉🐸
Congratulations to Sandra, Samantha @samnscience.bsky.social, Zhou, and our collaborators Tod Leighfield, Filizola lab @martafilizola.bsky.social, and Du Bois lab at Stanford.
www.nature.com/articles/s41...
Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins
Nature Communications - Dinoflagellates and cyanobacteria produce saxitoxin (STX) congeners that block voltage-gated sodium channels. Here authors show how amphibians may sequester STX congeners...
www.nature.com
April 24, 2025 at 6:04 PM
Reposted by Dr Samantha Nixon
I am working on a list of practical things that folks can do to help protect California amphibians, as part of a book project. Can you help me add to this list?

📷: Northwestern Salamander by Spencer Riffle
December 5, 2024 at 11:22 AM