Sameer Jauhar
@sameerjauhar.bsky.social
Clinical Reader in Affective Disorders and Psychosis, Division of Psychiatry, Department of Brain Siences, Imperial College London. Views very much my own.
So what?
Fair points- limbic selectivity for mood psychoses mapping onto therapeutic agents, and transdiagnostic approaches for positive symptoms?
I will take that, though happy for critique!
Fair points- limbic selectivity for mood psychoses mapping onto therapeutic agents, and transdiagnostic approaches for positive symptoms?
I will take that, though happy for critique!
August 14, 2025 at 11:38 PM
So what?
Fair points- limbic selectivity for mood psychoses mapping onto therapeutic agents, and transdiagnostic approaches for positive symptoms?
I will take that, though happy for critique!
Fair points- limbic selectivity for mood psychoses mapping onto therapeutic agents, and transdiagnostic approaches for positive symptoms?
I will take that, though happy for critique!
DA lowers in ppl w psychosis and MDE than ppl w mania (esp Mesolimbic system)
DA correlated w positive sx, across diagnoses (esp associative striatum)
Take home?
Symptoms track biology as opposed to diagnoses, though differences still exist across disorders.
DA correlated w positive sx, across diagnoses (esp associative striatum)
Take home?
Symptoms track biology as opposed to diagnoses, though differences still exist across disorders.
August 14, 2025 at 11:38 PM
DA lowers in ppl w psychosis and MDE than ppl w mania (esp Mesolimbic system)
DA correlated w positive sx, across diagnoses (esp associative striatum)
Take home?
Symptoms track biology as opposed to diagnoses, though differences still exist across disorders.
DA correlated w positive sx, across diagnoses (esp associative striatum)
Take home?
Symptoms track biology as opposed to diagnoses, though differences still exist across disorders.
Answers-look at the Figures, see what you think
August 14, 2025 at 11:38 PM
Answers-look at the Figures, see what you think
We used PET to examine dopamine synthesis in ppl w psychosis and mood disorders.
2 questions:
i) Is DA reduced in ppl w psychosis+ major depressive episode?
ii) Is there a relationship between DA and positive psychotic sx (delusions and hallucinations) across affective psychoses?
2 questions:
i) Is DA reduced in ppl w psychosis+ major depressive episode?
ii) Is there a relationship between DA and positive psychotic sx (delusions and hallucinations) across affective psychoses?
August 14, 2025 at 11:38 PM
We used PET to examine dopamine synthesis in ppl w psychosis and mood disorders.
2 questions:
i) Is DA reduced in ppl w psychosis+ major depressive episode?
ii) Is there a relationship between DA and positive psychotic sx (delusions and hallucinations) across affective psychoses?
2 questions:
i) Is DA reduced in ppl w psychosis+ major depressive episode?
ii) Is there a relationship between DA and positive psychotic sx (delusions and hallucinations) across affective psychoses?
What he would wish if he had a psychotic illness, and.....favourite pizza topping!
March 19, 2025 at 10:33 PM
What he would wish if he had a psychotic illness, and.....favourite pizza topping!
5:00 mins- “ I naively thought all novels were fiction”
“science is failure”
Just treat patients for a week and make a note every time you feel anxious, there is a research question there....."
“science is failure”
Just treat patients for a week and make a note every time you feel anxious, there is a research question there....."
March 19, 2025 at 10:33 PM
5:00 mins- “ I naively thought all novels were fiction”
“science is failure”
Just treat patients for a week and make a note every time you feel anxious, there is a research question there....."
“science is failure”
Just treat patients for a week and make a note every time you feel anxious, there is a research question there....."