Samantha Lapehn, PhD
@samanthalapehn.bsky.social
Research Scientist in the Paquette Lab at Seattle Children's Research Institute
Environmental Toxicology | Placenta | Omics | DOHaD | Redox Biology | Birth Defects
My Publications: tinyurl.com/SLapehn
LinkedIn: https://www.linkedin.com/in/samanthalapehn
Environmental Toxicology | Placenta | Omics | DOHaD | Redox Biology | Birth Defects
My Publications: tinyurl.com/SLapehn
LinkedIn: https://www.linkedin.com/in/samanthalapehn
New Paper evaluating prenatal organophosphate ester (OPE) exposure on the placental transcriptome in the CANDLE study. We investigated OPE metabolites individually and in mixture on placental genes & co-expressed gene modules.
www.sciencedirect.com/science/arti...
#placenta #environment #pregnancy
www.sciencedirect.com/science/arti...
#placenta #environment #pregnancy
An assessment of organophosphate ester mixtures and the placental transcriptome
Prenatal exposure to organophosphate ester (OPE) chemicals, commonly used as flame retardants and plasticizers, has been associated with adverse birth…
www.sciencedirect.com
March 27, 2025 at 4:10 PM
New Paper evaluating prenatal organophosphate ester (OPE) exposure on the placental transcriptome in the CANDLE study. We investigated OPE metabolites individually and in mixture on placental genes & co-expressed gene modules.
www.sciencedirect.com/science/arti...
#placenta #environment #pregnancy
www.sciencedirect.com/science/arti...
#placenta #environment #pregnancy
I’ll be presenting our work from the Paquette Lab on EDCs and microRNA expression in the CANDLE study this morning at SOT (Poster E273, 9:15-11:45am). #SOT2025
March 17, 2025 at 12:01 PM
I’ll be presenting our work from the Paquette Lab on EDCs and microRNA expression in the CANDLE study this morning at SOT (Poster E273, 9:15-11:45am). #SOT2025
Check out Mariana's first Paquette Lab paper on Vit D and the placental transcriptome
I am delighted to share the first paper to come out of my postdoc analyzing prenatal vitamin D levels measured at mid-pregnancy and delivery and their association with transcriptome-wide placental gene expression
doi.org/10.1016/j.tj...
doi.org/10.1016/j.tj...
Redirecting
doi.org
December 3, 2024 at 5:45 PM
Check out Mariana's first Paquette Lab paper on Vit D and the placental transcriptome
New Paper- We compared the transcriptome of bulk placental tissue from two ECHO cohorts to publicly available data from common in vitro placental models to see which experimental models most closely approximated the bulk tissue transcriptome.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
A Transcriptomic comparison of in vitro models of the human placenta
Selecting an in vitro culture model of the human placenta is challenging due to representation of different trophoblast cell types with distinct biolo…
www.sciencedirect.com
November 26, 2024 at 8:22 PM
New Paper- We compared the transcriptome of bulk placental tissue from two ECHO cohorts to publicly available data from common in vitro placental models to see which experimental models most closely approximated the bulk tissue transcriptome.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...